Results 41 to 50 of about 177,045 (348)

The Short-Chain Fatty Acids Propionate and Butyrate Augment Adherent-Invasive Escherichia coli Virulence but Repress Inflammation in a Human Intestinal Enteroid Model of Infection

open access: yesMicrobiology Spectrum, 2021
Short-chain fatty acids (SCFAs), which consist of six or fewer carbons, are fermentation products of the bacterial community that inhabits the intestine.
Fernanda Pace   +5 more
doaj   +1 more source

Altered propionate metabolism contributes to tumor progression and aggressiveness

open access: yesNature Metabolism, 2022
The alteration of metabolic pathways is a critical strategy for cancer cells to attain the traits necessary for metastasis in disease progression. Here, we find that dysregulation of propionate metabolism produces a pro-aggressive signature in breast and
Ana P. Gomes   +17 more
semanticscholar   +1 more source

Overexpression of GPR41 attenuated glucose production in propionate-induced bovine hepatocytes

open access: yesFrontiers in Veterinary Science, 2022
Bovine liver mainly utilizes the propionate as a gluconeogenic substrate to synthesize the glucose. However, the mechanism underlying the regulatory effects of propionate on the glucose production in bovine hepatocytes remains less known.
Miao Lin   +10 more
doaj   +1 more source

Syntrophic propionate-oxidizing bacteria in methanogenic systems

open access: yesFEMS Microbiology Reviews, 2021
The mutual nutritional cooperation underpinning syntrophic propionate degradation provides a scant amount of energy for the microorganisms involved, so propionate degradation often acts as a bottleneck in methanogenic systems.
M. Westerholm   +2 more
semanticscholar   +1 more source

The molecular mechanism of propionate-regulating gluconeogenesis in bovine hepatocytes [PDF]

open access: yesAnimal Bioscience, 2023
Objective Cows that are nursing get around 80% of their glucose from liver gluconeogenesis. Propionate, a significant precursor of liver gluconeogenesis, can regulate the key genes involved in hepatic gluconeogenesis expression, but its precise effects ...
Rui Pang   +7 more
doaj   +1 more source

Propionate alleviates myocardial ischemia-reperfusion injury aggravated by Angiotensin II dependent on caveolin-1/ACE2 axis through GPR41

open access: yesInternational Journal on Biological Sciences, 2022
Myocardial ischemia/reperfusion (I/R) injury is still a lack of effective therapeutic drugs, and its molecular mechanism is urgently needed. Studies have shown that the intestinal flora plays an important regulatory role in cardiovascular injury, but the
Fan Deng   +14 more
semanticscholar   +1 more source

Temporal Microbial Community Dynamics in Microbial Electrolysis Cells – Influence of Acetate and Propionate Concentration

open access: yesFrontiers in Microbiology, 2017
Microbial electrolysis cells (MECs) are widely considered as a next generation wastewater treatment system. However, fundamental insight on the temporal dynamics of microbial communities associated with MEC performance under different organic types with ...
Ananda Rao Hari   +4 more
doaj   +1 more source

Short-Chain Fatty Acid Propionate Protects From Hypertensive Cardiovascular Damage

open access: yesCirculation, 2018
Background: Arterial hypertension and its organ sequelae show characteristics of T cell–mediated inflammatory diseases. Experimental anti-inflammatory therapies have been shown to ameliorate hypertensive end-organ damage.
H. Bartolomaeus   +28 more
semanticscholar   +1 more source

Genomic reconstruction of short-chain fatty acid production by the human gut microbiota

open access: yesFrontiers in Molecular Biosciences, 2022
Short-chain fatty acids (SCFAs) including acetate, formate, propionate, and butyrate are the end products of dietary fiber and host glycan fermentation by the human gut microbiota (HGM).
Maria S. Frolova   +4 more
doaj   +1 more source

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