Results 71 to 80 of about 192,124 (377)

RNA-Seq-based transcriptome analysis of methicillin-resistant Staphylococcus aureus growth inhibition by propionate

Frontiers in Microbiology, 2022
Staphylococcus aureus is a pathogen that causes a variety of infectious diseases such as pneumonia, endocarditis, and septic shock. Methicillin-resistant S.
Jintaek Im, Dongwook Lee, Ok-Jin Park, Sathishkumar Natarajan, Junhyung Park, Cheol-Heui Yun, Cheol-Heui Yun, Seung Hyun Han   +7 more
doaj   +1 more source

Dietary supplementation with inulin-propionate ester or inulin improves insulin sensitivity in adults with overweight and obesity with distinct effects on the gut microbiota, plasma metabolome and systemic inflammatory responses: a randomised cross-over trial

Gut, 2019
Objective To investigate the underlying mechanisms behind changes in glucose homeostasis with delivery of propionate to the human colon by comprehensive and coordinated analysis of gut bacterial composition, plasma metabolome and immune responses. Design
E. Chambers, C. Byrne, D. Morrison, K. Murphy, T. Preston, Catriona Tedford, I. García-Pérez, Sofia Fountana, J. Serrano-Contreras, E. Holmes, C. Reynolds, Jordie F Roberts, R. Boyton, D. Altmann, J. McDonald, J. Marchesi, A. Akbar, N. Riddell, G. Wallis, G. Frost   +19 more
semanticscholar   +1 more source

Bioaugmentation of Overloaded Anaerobic Digesters Restores Function and Archaeal Community [PDF]

, 2015
Adding beneficial microorganisms to anaerobic digesters for improved performance (i.e. bioaugmentation) has been shown to decrease recovery time after organic overload or toxicity upset.
Maki, James, Tale, Vaibhav Panjabrao, Zitomer, Daniel   +2 more
core   +2 more sources

Is a Malleable Active Site Loop the Key to High Substrate Promiscuity? Hybrid, Biocatalytic Route to Structurally Diverse Taxoid Side Chains with Remarkable Dual Stereocontrol

Angewandte Chemie, EarlyView.
A highly stereoselective, dynamic reductive kinetic resolution (DYRKR) entry into myriad Taxotere‐like side chains with Clostridium acetobutylicum alcohol dehydrogenase (CaADH) enzyme is reported. Follow‐on cross couplings expand the structural diversity of the library (36 total examples).
Gaurav P. Kudalkar, Florian Leidner, Nivesh Kumar, Jared L. Hass, Peter Madzelan, Douglas R. Powell, Victor W. Day, Pierre Le Magueres, Joseph D. Ferrara, Lee M. Daniels, Akihito Yamano, Sho Ito, Wei Niu, Helmut Grubmüller, Mark A. Wilson, David B. Berkowitz   +15 more
wiley   +2 more sources

Cardiac Complications of Propionic and Other Inherited Organic Acidemias

Frontiers in Cardiovascular Medicine, 2020
Clinical observations and experimental studies have determined that systemic acid-base disturbances can profoundly affect the heart. A wealth of information is available on the effects of altered pH on cardiac function but, by comparison, much less is ...
Kyung Chan Park, Steve Krywawych, Eva Richard, Lourdes R. Desviat, Pawel Swietach   +4 more
doaj   +1 more source

Apple Pomace Modulates the Microbiota and Increases the Propionate Ratio in an In Vitro Piglet Gastrointestinal Model

Fermentation, 2022
Apple pomace (AP) contains biomolecules that induce changes in intestinal fermentation of monogastrics with positive expected health effects. The weaning of piglets can induce economic losses due to intestinal disturbances; new weaning strategies are ...
Sandrine Dufourny, Sarah Lebrun, Caroline Douny, Benjamin Dubois, Marie-Louise Scippo, José Wavreille, Pierre Rondia, Nadia Everaert, Véronique Delcenserie   +8 more
doaj   +1 more source

The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans

Science Translational Medicine, 2019
Propionate activates the insulin counter-regulatory hormonal response in mice, resulting in insulin resistance and weight gain. A metabolic dysregulator in hiding Propionate is a short-chain fatty acid that is a commonly used food preservative. Tirosh et
A. Tirosh, Ediz S. Calay, Gurol Tuncman, Kathryn C. Claiborn, K. Inouye, K. Eguchi, Michael Alcala, Moran Rathaus, K. Hollander, I. Ron, Rinat Livne, Y. Heianza, L. Qi, I. Shai, R. Garg, G. Hotamışlıgil   +15 more
semanticscholar   +1 more source

I.—On propione, the ketone of propionic acid [PDF]

Q. J. Chem. Soc.
n ...
openaire   +2 more sources

Exploring the Polymorphism of Drostanolone Propionate [PDF]

Molecules, 2020
2α-Methyl-4,5α-dihydrotestosterone 17β-propionate, known as drostanolone propionate or masteron, is a synthetic anabolic-androgenic steroid derived from dihydrotestosterone. The crystal structures of two polymorphs of drostanolone propionate have been determined by single crystal X-ray diffraction and both crystallizes in the monoclinic crystal system.
Gheorghe Borodi, Alexandru Turza, Attila Bende   +2 more
openaire   +4 more sources

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source