Results 51 to 60 of about 218,446 (354)

Discharge Readiness after Propofol with or without Dexmedetomidine for Colonoscopy: A Randomized, Controlled Trial.

Anesthesiology, 2019
WHAT WE ALREADY KNOW ABOUT THIS TOPIC It is unknown whether adding low-dose dexmedetomidine to propofol for colonoscopies enhances hemodynamic stability without prolonging recovery WHAT THIS ARTICLE TELLS US THAT IS NEW: One hundred and one patients were
L. Edokpolo, Daniel Mastriano, J. Serafin, J. Weedon, Maryam T Siddiqui, D. Dimaculangan   +5 more
semanticscholar   +1 more source

Incidence of tolerance in children undergoing repeated administration of propofol for proton radiation therapy: a retrospective study

BMC Anesthesiology, 2018
Background Propofol is an excellent hypnotic drug for use in repeated radiation procedures in young children. To date, tolerance to propofol generally does not develop in pediatric patients undergoing radiation therapy.
RyungA Kang, Byung Seop Shin, Young Hee Shin, Nam-Su Gil, Ye Na Oh, Ji Seon Jeong   +5 more
doaj   +1 more source

A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration [PDF]

, 2007
This was a prospective randomized double blind controlled study to compare intubating conditions at 60 seconds with rocuronium 0.6 mg/kg by using three different induction techniques: propofol-placebo (PP), propofol-ephedrine (PE) and propofol ...
Karis Misiran,, Muhd Helmi Azmi,
core  

Methotrexate‐Loaded Liposomal Formulation Enables 6‐Week Sustained Intraocular Therapeutic Drug Release in a Porcine Model

Advanced Healthcare Materials, EarlyView.
A liposomal formulation for methotrexate enables minimally invasive, sustained intraocular drug delivery for over six weeks with a single injection. Developed for treating intraocular diseases like lymphoma and PVR, it offers excellent biocompatibility in vivo in a porcine model.
Maximilian Hammer, Lea Skrzypczyk, Sabrina Wohlfart, Bryan Calder Ackermann, Ludwig Geisweid, Simon William Pohl, Margarita Karaivanova, Jonathan Herth, Victor Aristide Augustin, Alexander Studier‐Fischer, Tina Sackmann, Leon Kaulen, Anna Steyer, Walter Mier, David H Steel, Kanmin Xue, Gerd Uwe Auffarth, Philipp Uhl   +17 more
wiley   +1 more source

Propofol inhibits proliferation and epithelial-mesenchymal transition of MCF-7 cells by suppressing miR-21 expression

Artificial Cells, Nanomedicine, and Biotechnology, 2019
Breast cancer is a common malignant tumor with a high incidence of recurrence and metastasis. It has been reported that propofol has certain anti-breast cancer effects, but the intrinsic molecular mechanism remains unclear.
Qing Du, Xuezhi Zhang, Xin Zhang, Ming Wei, Hongmei Xu, Shilei Wang   +5 more
doaj   +1 more source

The effects of repeated propofol anesthesia on spatial memory and long-term potentiation in infant rats under hypoxic conditions

Genes and Diseases, 2020
Propofol is widely used as an intravenous drug for induction and maintenance in general anesthesia. Hypoxemia is a common complication during perianesthesia.
Mang Sun, Ruixue Yuan, Hui Liu, Jing Zhang, Shengfen Tu   +4 more
doaj   +1 more source

The Impact of Age on Propofol Requirement for Inducing Loss of Consciousness in Elderly Surgical Patients

Frontiers in Pharmacology, 2022
It is generally accepted that geriatric patients are more sensitive to propofol than adults; thus, a dose-adjusted propofol is recommended for these patients during the induction of anesthesia.
Hua Yang, Hui-Min Deng, Hai-Yan Chen, Shu-Heng Tang, Fang Deng, Yu-Gang Lu, Jin-Chao Song   +6 more
doaj   +1 more source

Propofol inhibits parthanatos via ROS–ER–calcium–mitochondria signal pathway in vivo and vitro

Cell Death and Disease, 2018
Parthanatos is a new form of programmed cell death. It has been recognized to be critical in cerebral ischemia–reperfusion injury, and reactive oxygen species (ROS) can induce parthanatos.
Hanhui Zhong, Rui Song, Qiongni Pang, Yawei Liu, Jinling Zhuang, Yeming Chen, Jijie Hu, Jian Hu, Youtan Liu, Zhifeng Liu, Jing Tang   +10 more
semanticscholar   +1 more source

Inhibiting Liver‐Derived C3 Protein Rescues Anesthesia/Surgery‐Induced Cognitive Impairment, Synaptic Disorders, and Microglial Phagocytosis

Advanced Science, EarlyView.
This study provides evidence that anesthesia/surgery can induce the BBB breakdown and promote the release of hepatogenous C3 protein into the blood. This surgical dual factors ultimately drove C3 to cross the damaged BBB and selectively colocalize with C3aR in the hippocampus, which results in structural and functional injury of synapse, C3aR‐mediated ...
Qianqian Wu, Peilin Cong, Zhouxiang Li, Yuxin Zhang, Huanghui Wu, Qian Zhang, Yawei Li, Li Tian, Qingyuan Miao, Yinggang Zheng, Hui Zhang, Qian Chen, Enduo Feng, Xinyang Li, Zheping Chen, Dong‐Xin Wang, Xinwei Huang, Lize Xiong   +17 more
wiley   +1 more source

The Effect of Sevoflurane Plus Propofol on Pain and Complications after Laminectomy: A Randomized Double Blind Clinical Trial [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Pain is one of the most important reasons for the patients concern after surgery. The perfect sedative should have properties like rapid onset, least pain and adverse effects.
Aminolah Vasigh, Fatemeh Najafi, Molouk Jaafarpour, Javaher Khajavikhan, Ali Khani   +4 more
doaj   +1 more source