Results 61 to 70 of about 218,446 (354)

Frequency of Predisposing Factor of Nausea and Vomiting After Chest Surgery Under General Anaesthesia [PDF]

open access: yes, 2019
Background: Postoperative nausea and vomiting are common and distressing postsurgical symptoms. These symptoms are of particular concern in outpatient surgery because they may require additional direct resources, such as supplies and antiemetic ...
Bhatti, S. U. (Sami)   +5 more
core   +2 more sources

Metabolic Profiles of Propofol and Fospropofol: Clinical and Forensic Interpretative Aspects

open access: yesBioMed Research International, 2018
Propofol is an intravenous short-acting anesthetic widely used to induce and maintain general anesthesia and to provide procedural sedation. The potential for propofol dependency and abuse has been recognized, and several cases of accidental overdose and
R. Dinis-Oliveira
semanticscholar   +1 more source

Concrete Structure Inspired 3D‐Printed Framework Mechanically Reinforced Zwitterionic Hydrogel for Efficient Postoperative Abdominal Adhesion Prevention

open access: yesAdvanced Science, EarlyView.
Inspired by the establishment process and structure of concrete, a 3D‐printed PCL framework‐reinforced composite hydrogel is developed to overcome the mechanical limits of the original zwitterionic hydrogel toward clinic application of postoperative adhesion prevention.
Jianguo Song   +4 more
wiley   +1 more source

Conformational variability of the glycine receptor M2 domain in response to activation by different agonists [PDF]

open access: yes, 2007
Models describing the structural changes mediating cys-loop receptor activation generally give little attention to the possibility that different agonists may promote activation via distinct M2 pore-lining domain structural rearrangements.
Akabas   +30 more
core   +3 more sources

Propofol for gastrointestinal endoscopy

open access: yesUnited European Gastroenterology journal, 2018
Most gastrointestinal endoscopic procedures are now performed with sedation. Moderate sedation using benzodiazepines and opioids continues to be widely used, but propofol sedation is becoming more popular because its unique pharmacokinetic properties ...
T. Nishizawa, Hidekazu Suzuki
semanticscholar   +1 more source

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

open access: yesAdvanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera   +12 more
wiley   +1 more source

Sedation-Analgesia in Elective Colonoscopy: Propofol-Fentanyl Versus Propofol-Alfentanil

open access: yesBrazilian Journal of Anesthesiology, 2013
Background and objectives: Sedation-analgesia is recommended for comfortable colonoscopy procedures, which are invasive and can be painful. This study aimed to compare the combinations of propofol-alfentanil and propofol-fentanyl for sedation-analgesia ...
Hacer Şebnem Türk   +5 more
doaj   +1 more source

The influence of storage time and temperature on propofol concentrations in canine blood and plasma [PDF]

open access: yesPeerJ, 2017
Propofol is an intravenous anesthetic commonly used due to its favorable pharmacokinetic and pharmacodynamic profile. There are discrepancies in the literature about the most appropriate sample for determining propofol concentrations. Although plasma has
Sherry Cox   +4 more
doaj   +2 more sources

SIRT3 Enhances the Protective Role of Propofol in Postoperative Cognitive Dysfunction via Activating Autophagy Mediated by AMPK/mTOR Pathway

open access: yesFrontiers in Bioscience-Landmark, 2022
Background: Postoperative cognitive dysfunction (POCD) is a common complication after surgery and anesthesia. In this study, we aimed to determine the neuroprotective mechanism of Sirtuin 3 (SIRT3) and propofol in POCD. Methods: The cognitive dysfunction
Shang Li   +7 more
doaj   +1 more source

A novel multivariate STeady-state index during general ANesthesia (STAN) [PDF]

open access: yes, 2017
The assessment of the adequacy of general anesthesia for surgery, namely the nociception/anti-nociception balance, has received wide attention from the scientific community. Monitoring systems based on the frontal EEG/EMG, or autonomic state reactions (e.
A Albertin   +34 more
core   +1 more source

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