Results 71 to 80 of about 149 (146)
Abstract Objective The STEPPER (Status Epilepticus in Emilia‐Romagna) study aimed to investigate the clinical characteristics, prognostic factors, and treatment approaches of status epilepticus (SE) in adults of the Emilia‐Romagna region (ERR), Northern Italy.
Lidia Di Vito+56 more
wiley +1 more source
Abstract Objective Generalized tonic–clonic seizures (GTCS) are considered to be among the most devastating seizures due to increased health risks. Use of device‐based therapies, such as vagus nerve stimulation (VNS), is common for those resistant to antiseizure medications and important for those in whom resective surgery is not feasible.
Ana Suller Marti+9 more
wiley +1 more source
Synaptic inhibitory dynamics drive benzodiazepine response in pediatric status epilepticus
Abstract Objective Pediatric status epilepticus (SE) is a medical emergency associated with significant morbidity. Benzodiazepines (BZPs) are the current first‐line treatment, but do not work in more than one third of children presenting with SE. Animal studies have shown that SE can cause changes in synaptic inhibition signaling that can ultimately ...
Tommaso Fedele+5 more
wiley +1 more source
Changes in cortical delta power during chronic invasive epilepsy monitoring
Abstract Objective Cortical delta band (1–4 Hz) activity is considered a biomarker for states of altered consciousness, with increased delta power observed during anesthesia, sleep, coma, and delirium. The current study sought to characterize delta power following electrode implantation with respect to patient demographics and clinical characteristics ...
Emily R. Dappen+4 more
wiley +1 more source
Status epilepticus in older adults: A critical review
Abstract Older adults (≥60 years of age) have the highest incidence of status epilepticus (SE) among adults and experience the highest morbidity and mortality. SE incidence increases with age in adulthood. A recent study from Austria estimated an incidence of 89.6/100 000 and 67.6/100 000 person‐years adjusted for age and sex in women and men aged >60 ...
Matthew R. Woodward+5 more
wiley +1 more source
Muscle transposition graft for closure of a permanent tracheostoma in a Quarter Horse mare
Summary Permanent tracheostomy is sometimes required in horses with severe and irreversible obstructive upper airway conditions. Abnormal respiratory noise and altered vocalisation may be of concern to owners and its influence on mare‐foal recognition and bonding should be considered.
G. P. Stemmet, R. Labens
wiley +1 more source
ABSTRACT Background Bullous pemphigoid (BP) is the most common autoimmune blistering disease, with a rising incidence in the elderly. BP is associated with multiple triggering factors, including drug exposure. However, evidence in this respect is limited, and the underlying immune mechanisms remain unknown.
Belen de Nicolas‐Ruanes+17 more
wiley +1 more source
Integrated pulmonary index during procedural sedation and analgesia: A cluster‐randomized trial
Abstract Aim To evaluate the effectiveness of utilizing the integrated pulmonary index for capnography implementation during sedation administered by nurses. Design Cluster‐randomized trial. Methods Participants were enrolled from the interventional radiology department at an academic hospital in Canada.
Aaron Conway+4 more
wiley +1 more source
Patient Agitation in the Intensive Care Unit: A Concept Analysis
ABSTRACT Aim Exploring the concept of patient agitation in the intensive care unit. Background Patient agitation in the intensive care unit is of widespread concern and linked to negative outcomes for patients, staff, and family members. There is currently no consensus on what constitutes agitation in the intensive care context, hindering effective and
Anne Mette N. Adams+7 more
wiley +1 more source