Results 151 to 160 of about 38,575 (293)

Impact of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors on Lipoprotein(a)

JACC: Advances
Background: Lipoprotein(a) [Lp(a)] has been independently associated with increased cardiovascular risk. Objectives: The authors examined the effect of monoclonal antibody proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9is) on plasma Lp(a)
Frederick Berro Rivera, MD, Sung Whoy Cha, MD, Cruz Linnaeus Louisse, MD, Genquen Philip Carado, MD, John Vincent Magalong, MD, Vincent Anthony Tang, MD, Mary Grace Enriquez, MD, Martha Gulati, MD, MS, Byambaa Enkhmaa, MD, PhD, Neha Pagidipati, MD, MPH, Nishant P. Shah, MD   +10 more
doaj  

PCSK9: a convertase that coordinates LDL catabolism

Journal of Lipid Research, 2009
The identification and characterization of proprotein convertase subtilisin-like/kexin type 9 (PCSK9) have provided new insights into LDL metabolism and the causal role of LDL in coronary heart disease (CHD).
Jay D. Horton, Jonathan C. Cohen, Helen H. Hobbs   +2 more
doaj  

The role of proprotein convertase subtilisin/kexin type 9 inhibitors in managing cardiovascular risk [PDF]

, 2016
Hypercholesterolaemia and dyslipidaemia, marked by decreased levels of high-density lipoprotein and elevated levels of lowdensity lipoprotein (LDL), increase the risk of cardiovascular disease.
Bronkhorst, E, Schellack, Gustav, Schellack, Natalie   +2 more
core   +1 more source

Specific and Transient Up-Regulation of Proprotein Convertase 6 at the Site of Embryo Implantation and Identification of a Unique Transcript in Mouse Uterus During Early Pregnancy1 [PDF]

, 2003
Guiying Nie, Ying Li, Hiroyuki Minoura, Jock K. Findlay, Lois A. Salamonsen   +4 more
openalex   +1 more source

PACE4 (PCSK6): another proprotein convertase link to iron homeostasis?

Haematologica, 2015
Johann Guillemot, Nabil G. Seidah
doaj   +1 more source

The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): Liver regeneration and neuronal differentiation [PDF]

, 2003
Nabil G. Seidah, Suzanne Benjannet, L. Alexandra Wickham, Jadwiga Marcinkiewicz, Stéphanie Bélanger Jasmin, Stefano Stifani, Ajoy Basak, Annik Prat, Michel Chrètien   +8 more
openalex   +1 more source

Membrane Type-1 Matrix Metalloproteinase Functions as a Proprotein Self-convertase [PDF]

, 2003
Dmitri V. Rozanov, Alex Y. Strongin
openalex   +1 more source

The secretory proprotein convertases furin, PC5, and PC7 activate VEGF-C to induce tumorigenesis [PDF]

, 2003
Géraldine Siegfried, Ajoy Basak, James A. Cromlish, Suzanne Benjannet, Jadwiga Marcinkiewicz, Michel Chrètien, Nabil G. Seidah, Abdel‐Majid Khatib   +7 more
openalex   +1 more source

Proprotein convertase subtilisin/kexin 9 inhibitors in reducing cardiovascular outcomes:A systematic review and meta-analysis [PDF]

, 2019
Du, Heyue, Gao, Haihui, Hao, Xiaoting, Kwong, Joey S. W., Lang, Chim, Li, Jianshu, Li, Ling, Li, Qianrui, Li, Sheyu, Li, Xiaodan, Mordi, Ify, Nemeth, Imola, Rao, Li, Su, Na, Tian, Haoming, Vandvik, Per Olav, Yang, Xueli, Zhang, Longhao   +17 more
core   +2 more sources

The Proprotein Convertase PC5A and a Metalloprotease Are Involved in the Proteolytic Processing of the Neural Adhesion Molecule L1 [PDF]

, 2003
Ina Kalus, Birthe Schnegelsberg, Nabil G. Seidah, Ralf Kleene, Melitta Schachner   +4 more
openalex   +1 more source