Results 121 to 130 of about 36,320 (224)

Observed Weight Gain in Patients With Pulmonary Arterial Hypertension Treated With Sotatercept. [PDF]

Pulm Circ
Greene RA, Tat D, Sherman-Roe A, Cayton T, Lopes J, Jorrin A, Klinger J, Mullin CJ, Needle K, Oldham WM, Osgood C, Singh N, Ventetuolo CE.   +12 more
europepmc   +1 more source

Antimitogenesis by prostacyclin linked to regulation of Skp2 gene expression

, 2004
Atherosclerosis and restenosis are proliferative vascular diseases involving, in part, deregulated vascular smooth muscle cell proliferation. The dysfunction of endothelial cells plays a critical role in the early pathogenesis of atherosclerosis, and the
Stewart, Sheryl A
core  

Sotatercept Rescue Therapy for Acute Right Heart Failure in HIV-Associated PAH. [PDF]

Pulm Circ
Li Y, Grund D, Kremer N, Müller-Redetzky H, Zajonz M, Gaebler C, Witzenrath M, Olschewski H, Yogeswaran A.   +8 more
europepmc   +1 more source

New trends in thromboxane and prostacyclin modulators

, 2000
Thromboxane A2 (TXA2) and prostacyclin (PGI2) are two labile products formed from arachidonic acid by the way of cyclooxygenase. An overproduction of thromboxane A2 has been detected in a series of diseases whereby this prostanoid is assumed to ...
Delarge, J, David, J L, de Leval, X, Masereel, B, Dogné, Jean-Michel   +4 more
core  

Therapeutic Potential of Treprostinil Inhalation Powder for Patients with Pulmonary Arterial Hypertension: Evidence to Date

Drug, Healthcare and Patient Safety
Steven J Cassady,1 Jose Alejandro N Almario,2 Gautam V Ramani3 1Division of Pulmonary & Critical Care Medicine, University of Maryland School of Medicine, Baltimore, MD, USA; 2Department of Internal Medicine, University of Maryland School of Medicine ...
Cassady SJ, Almario JAN, Ramani GV
doaj  

In Vitro Effects of Minor Olive Oil Compounds on Prostacyclin/Thromboxane Balance Under Acute High-Glucose Conditions. [PDF]

Biomolecules
Sánchez-Tévar AM, Ortega-Hombrados L, Rodríguez-Pérez MD, Arrebola-Ramírez MM, Martín-Aurioles E, Pérez-Burillo S, Verdugo-Cabello C, Cobos-López R, Cruz JP, González-Correa JA.   +9 more
europepmc   +1 more source

Exploring the therapeutic landscape of pulmonary hypertension associated with interstitial lung disease, with a focus on idiopathic pulmonary fibrosis: a narrative review. [PDF]

Front Pharmacol
Reccardini N, Da Re B, Mondini L, Salton F, Confalonieri M, Confalonieri P, Hughes M, Monteleone G, Ruaro B.   +8 more
europepmc   +1 more source

Food Effects on the Pharmacokinetics of Single Dose and Steady-State Ralinepag, a Novel Oral Prostacyclin Agonist, in Healthy Volunteers. [PDF]

Am J Cardiovasc Drugs
Lachant D, Botta CE, Giannakoulas G, Patzlaff N, Seaman S, Broderick M, Guido M, Mellemkjær S, Safdar Z.   +8 more
europepmc   +1 more source

The Evolving Landscape of Pulmonary Hypertension Treatment: From Vasodilation to Disease Modification. [PDF]

Clin Transl Sci
Ayalasomayajula S, Bajwa EK, Cornell AG, Loureiro MJ, Kim SS, DiBello JR, Sterner E, Chen R, Younis IR.   +8 more
europepmc   +1 more source

Sotatercept as a Therapeutic Option for Systemic Sclerosis-Associated Pulmonary Arterial Hypertension With Features of PVOD/PCH. [PDF]

Pulm Circ
Nishioka Y, Imanishi K, Matsuda E, Nakamura W, Shirayanagi R, Ojiro H, Katagiri A.   +6 more
europepmc   +1 more source