Results 101 to 110 of about 36,320 (224)

Catalytic asymmetric formal synthesis of beraprost

open access: yesBeilstein Journal of Organic Chemistry, 2015
The first catalytic asymmetric synthesis of the key intermediate for beraprost has been achieved through an enantioselective intramolecular oxa-Michael reaction of an α,β-unsaturated amide mediated by a newly developed benzothiadiazine catalyst.
Yusuke Kobayashi   +2 more
doaj   +1 more source

Stroke in Pregnancy and Preeclampsia: Effect of Low‐Dose Aspirin Treatment on Collateral Flow Velocity and Cerebral Blood Flow Autoregulation During Ischemia in Rats

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Experimental preeclampsia (ePE) has been shown to have worsened outcome from stroke. We investigated the effect of low‐dose aspirin, known to prevent preeclampsia, on stroke hemodynamics and outcome, and the association between the ...
Marilyn J. Cipolla, Sarah M. Tremble
doaj   +1 more source

Partial isolation and function of the prostacyclin regulating plasma factor

open access: yes, 1985
Rat aortic rings stop producing prostacyclin upon prolonged washing in buffer. This 'exhaustion' is caused by inhibition of cyclo-oxygenase, since these rings still convert cyclic endoperoxides but not arachidonic acid into prostacyclin, and most ...
D'Hondt, L.   +8 more
core   +1 more source

Anticoagulation strategies for pediatric continuous renal replacement therapy

open access: yesJournal of Pediatric Critical Care
Continuous renal replacement therapy (CRRT) in children is quite challenging to manage because of their increased propensity for circuit clotting. The anticoagulant strategies are paramount in reducing the downtime in pediatric CRRT.
Aakash Chandran Chidambaram   +2 more
doaj   +1 more source

Prostacyclin for pulmonary hypertension in adults

open access: yes, 2005
Prostacyclin may benefit patients with pulmonary hypertension (raised blood pressure in the lungs) in the short term but studies longer in duration are required.
Paramothayan, N Shanthi   +3 more
core   +1 more source

Use of Dupilumab to Treat Cutaneous Complications of Continuous Prostacyclin Infusion in Pulmonary Hypertension: A Case Report and Review of Literature

open access: yesPulmonary Circulation
Adhesive reactions are common complications of continuous treprostinil infusions, limiting their recommended use as a treatment for severe pulmonary hypertension.
Nidhy P. Varghese   +4 more
doaj   +1 more source

Prostanoid therapies in the management of pulmonary arterial hypertension

open access: yesTherapeutics and Clinical Risk Management, 2015
Barbara L LeVarge Department of Pulmonary and Critical Care Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA Abstract: Prostacyclin is an endogenous eicosanoid produced by endothelial cells; through actions on vascular smooth-muscle ...
LeVarge BL
doaj  

Prostacyclin release from the rat isolated heart

open access: yes, 1982
Prostacyclin release from the rat isolated ...
GJ Dusting (15839609)   +1 more
core  

Thromboxane-prostacyclin balance and platelet aggregability in patients with minor cardiac abnormalities

open access: yesТерапевтический архив, 2010
Aim. To reveal changes in the thromboxane-prostacyclin balance and platelet aggregability in patients with various variants of minor cardiac abnormalities. Subjects and methods: Six-five patients (mean age 23.0±0.7 years) with minor cardiac abnormalities
Aleksandr Valentinovich Yagoda   +3 more
doaj  

Mol Pharmacol 62:1103–1111, 2002 Printed in U.S.A. Pharmacophore Definition and Three-Dimensional Quantitative Structure-Activity Relationship Study on Structurally Diverse

open access: yes, 2002
Prostacyclin is an endogenous mediator that shows potent platelet inhibitory activity and powerful relaxation of peripheral resistance vessels. Prostacyclin receptor agonists are valuable drugs in the treatment of various vascular diseases spanning ...
Friederike Stoll   +5 more
core  

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