Journal of Comparative Neurology, Volume 534, Issue 8, August 2026.Two lateral mouse brain sagittal sections labeled, respectively, for Lypd1 (A) and Kcnab3 (B). (A) Lypd1 labels positively cortical Layers 2 and 5 (less heavily), but only at limbic mesocortical sites, forming the limbic ring that separates the unlabeled isocortex (IsoCx) from the unlabeled hippocampal and olfactory allocortex (Hi, Sub, ERh; OlfCx ...
Luis Puelles, Elena Garcia‐Calero
wiley +1 more source
Topical prostaglandin analogues and conjunctival inflammation in uveitic glaucoma. [PDF]
, 2012 20.02.14 KB. Ok to add published verson to spiral, OA paper.A pilot study to determine whether topical prostaglandin analogues alter the expression of conjunctival inflammatory markers in patients with uveitic glaucoma.Prospective, single-masked case ...
Sallam, A +3 more
core +1 more source
Investigating the Antidiabetic Effects of Calotropis procera: Preclinical Assessment
Food Science &Nutrition, Volume 14, Issue 8, August 2026.Calotropis Procera In vitro/Diabetic rodent model Improved β‐cell function, reduced hepatic gluconeogenesis antioxidant activity. ABSTRACT Diabetes mellitus (DM) is a metabolic disease characterized by persistent hyperglycemia, oxidative stress, and inflammation, often leading to severe complications.
Yu‐Cheng Kuo +10 more
wiley +1 more source
The cyclic AMP response element plays an essential role in the expression of the human prostaglandin-endoperoxide synthase 2 gene in differentiated U937 monocytic cells [PDF]
, 1994 The promoter activity of 1432 bp upstream of the human prostaglandin-endoperoxide synthase 2 gene (PTGS2) was examined in differentiated U937 monocytic cells expressing prostaglandin-endoperoxide synthase 2 mRNA.
Inoue, Hiroyasu +9 more
core +1 more source
Prostaglandin endoperoxide synthase. The aspirin acetylation region.
Journal of Biological Chemistry, 1992 Aspirin selectively acetylates Ser-530 of prostaglandin endoperoxide (PGH) synthase-1. This causes inactivation of the cyclooxygenase activity of the enzyme, but does not appreciably affect its peroxidase activity. Although the aspirin-acetylated enzyme is inactive, we found that PGH synthase-1 in which Ser-530 had been replaced with an alanine was ...
T, Shimokawa, W L, Smith
openaire +2 more sources
Prostaglandin E Synthases in Zebrafish
, 2005 Pini B, Grosser T, Lawson JA, Price TS, Pack MA, FitzGerald GA. Prostaglandin E Synthases in Zebrafish. Arteriosclerosis, Thrombosis, and Vascular Biology.
Grosser, Tilo ; https://orcid.org/ +5 more
core +1 more source
Thromboxane and Stable Prostaglandin Endoperoxide Analogs Stimulate Water Permeability in the Toad Urinary Bladder [PDF]
, 1980 The effects of thromboxane B2 and the stable prostaglandin endoperoxide analogs (15Z)-hydroxy - 9α - 1 lα - (epoxymethano)prosta - 5Z,13E – dienoic acid (U44069) and (15Z)-hydroxy-1 lα,9α-(epoxymethano) prosta-5Z,13E-dienoic acid (U46619) were tested on ...
Halushka, Perry V. +3 more
core +1 more source
, 1986 The use of enzyme inhibitors to clarify the role of thromboxane A2 in vasoocclusive disease has been complicated by their non-specific action. To address this problem we have examined the effects of thromboxane A2/prostaglandin endoperoxide receptor ...
Desmond J. Fitzgerald +7 more
core +1 more source
Prostaglandin E Positively Modulates Endothelial Progenitor Cell Homeostasis: An Advanced Treatment Modality for Autologous Cell Therapy [PDF]
, 2009 Aims: The mobilization of endothelial progenitor cells (EPC) and their functioning in postnatal neovascularization are tightly regulated. To identify new modulators of EPC homeostasis, we screened biologically active prostaglandin E compounds for their ...
Hermann, Patrick C. +6 more
core +1 more source
Regulation of microsomal prostaglandin E2 synthase by cyclopentenone prostaglandins in colon cancer cells [PDF]
, 2006 Prostaglandin E2 is the major prostaglandin involved in colorectal carcinogenesis. The biosynthesis of prostaglandin E2 is accomplished by several terminal prostaglandin E synthases through catalytical conversion of the cyclooxygenase product ...
Yudina, Yulyana
core