Results 31 to 40 of about 2,413 (136)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, Volume 16, Issue 7, Page 1328-1339, July 2026.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Prostaglandin endoperoxide synthase. The aspirin acetylation region.

Journal of Biological Chemistry, 1992
Aspirin selectively acetylates Ser-530 of prostaglandin endoperoxide (PGH) synthase-1. This causes inactivation of the cyclooxygenase activity of the enzyme, but does not appreciably affect its peroxidase activity. Although the aspirin-acetylated enzyme is inactive, we found that PGH synthase-1 in which Ser-530 had been replaced with an alanine was ...
T, Shimokawa, W L, Smith
openaire   +2 more sources

Prostaglandin Endoperoxide H Synthases [PDF]

Journal of Biological Chemistry, 2007
Jiayan Liu, Steve A. Seibold, Caroline J. Rieke, Inseok Song, Robert I. Cukier, William L. Smith   +5 more
openaire   +1 more source

Prostaglandin Endoperoxide H Synthase-1 [PDF]

Journal of Biological Chemistry, 2001
Elizabeth D. Thuresson, Karen M. Lakkides, Caroline Jill Rieke, Ying Sun, Byron A. Wingerd, Renée Micielli, Anne M. Mulichak, Michael G. Malkowski, R. Michael Garavito, William L. Smith   +9 more
openaire   +1 more source

Nonselective inhibition of prostaglandin-endoperoxide synthases by naproxen ameliorates acute or chronic liver injury in animals. [PDF]

Exp Mol Pathol, 2014
Bahde R, Kapoor S, Gupta S.
europepmc   +1 more source

JBC reviews tribute to the memory of Dr William (Bill) Smith (1945-2024). [PDF]

J Biol Chem
Carman GM.
europepmc   +1 more source

An environmentally relevant phthalate mixture impairs ovulatory prostaglandin and progesterone receptor pathways in human granulosa cells in vitro. [PDF]

Environ Int
Land KL, Xu H, Akin JW, Hannon PR.
europepmc   +1 more source

Stimulation of Transient Receptor Potential Channels TRPM3 and TRPM8 Increases Human Prostaglandin Endoperoxide Synthase-2 Promoter Activity. [PDF]

Molecules
Brandmeier N, Rössler OG, Thiel G.
europepmc   +1 more source

The Role of Prostaglandins as Major Inflammatory Mediators in Colorectal Cancer. [PDF]

Int J Mol Sci
Macia Guardado M, Lutz V, Hengstschläger M, Dolznig H.   +3 more
europepmc   +1 more source

Geraniol Exerts Cytotoxic Effects in Red Cells Through Ca²⁺ Elevation and Membrane Hyperpolarization: Attenuating Effects of COX/CK1α/Rac1 GTPase Inhibition. [PDF]

Molecules
Alfhili MA, Alruwaili SH, Alsughayyir J.
europepmc   +1 more source