Results 11 to 20 of about 4,137 (180)

Prostaglandin pathways in equine myometrium regulations: endometrosis progression [PDF]

Frontiers in Veterinary Science
IntroductionProstaglandins (PG) are important regulators of the myometrial contractility in mammals. Endometrosis, a condition characterized by morphological changes in the equine endometrium, also affects endometrial secretory function.
Katarzyna K. Piotrowska-Tomala, Anna Z. Szóstek-Mioduchowska, Ewa M. Drzewiecka, Ewa M. Drzewiecka, Agnieszka W. Jonczyk, Anna Wójtowicz, Michał H. Wrobel, Graca Ferreira-Dias, Graca Ferreira-Dias, Dariusz J. Skarzynski   +9 more
doaj   +2 more sources

Allosteric regulation of prostaglandin endoperoxide H₂ synthases. [PDF]

J Biol Chem
Prostaglandin Endoperoxide H2 Synthases (PGHS-1 and PGHS-2), also referred to as cyclooxygenases (COX-1 and COX-2), are homodimeric enzymes that oxygenate arachidonic acid (AA) to generate Prostaglandin H2 (PGH2), the precursor to prostaglandins, prostacyclin, and thromboxane.
Dong L, Malkowski MG.
europepmc   +3 more sources

Prostaglandin Endoperoxide H Synthases (Cyclooxygenases)-1 and −2 [PDF]

Journal of Biological Chemistry, 1996
R Michael Garavito
exaly   +3 more sources

The Expression Pattern of Prostaglandin-Endoperoxide Synthase-2 in Immature Oocytes and Surrounding Cumulus Cells May Explain A Disrupted Oocyte Maturation Process

Gynecology Obstetrics & Reproductive Medicine, 2021
Objective: To evaluate the correlation between the gene expression of prostaglandin-endoperoxide synthase-2 in the cumulus-oocyte complex with the level of prostaglandin-endoperoxide synthase-2 in follicular fluid and follicle diameter, oocyte ...
Goktan Kuspinar, Berrin Avcı
doaj   +1 more source

Cyclooxygenase-2 expression in cervical cancer [PDF]

Vojnosanitetski Pregled, 2014
Background/Aim. Cyclooxygenase (COX) or prostaglandin H2 synthase is the first enzyme that catalyzes the first two steps in the biosynthesis of prostaglandins from arachidonic acid.
Mandić Aljoša, Ušaj-Knežević Slavica, Ivković-Kapicl Tatjana, Ninčić Dejan, Malenković Goran   +4 more
doaj   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Effects of ibuprofen enantiomers and its coenzyme A thioesters on human prostaglandin endoperoxide synthases [PDF]

British Journal of Pharmacology, 1997
Neupert W, Brugger R, Euchenhofer C, Brune K, Geisslinger G.   +4 more
exaly   +2 more sources

Selective COX-2 inhibitors and risk of myocardial infarction [PDF]

, 2005
Selective inhibitors of cyclooxygenase- 2 ( COX- 2, ` coxibs') are highly effective anti-inflammatory and analgesic drugs that exert their action by preventing the formation of prostanoids.
Klauss, V., Krotz, F., Schiele, T. M., Sohn, Hae-Young   +3 more
core   +1 more source

Nitro-fatty acids: novel anti-inflammatory lipid mediators

Brazilian Journal of Medical and Biological Research, 2013
Nitro-fatty acids are formed and detected in human plasma, cell membranes, and tissue, modulating metabolic as well as inflammatory signaling pathways.
H. Rubbo
doaj   +1 more source

Vasoconstrictor prostanoids [PDF]

, 2010
In cardiovascular diseases and during aging, endothelial dysfunction is due in part to the release of endothelium-derived contracting factors that counteract the vasodilator effect of the nitric oxide.
Félétou, M, Huang, Y, Vanhoutte, PM
core   +1 more source