Results 11 to 20 of about 69,164 (164)

Prostaglandin endoperoxide synthase contains an EGF‐like domain [PDF]

FEBS Letters, 1989
Prostaglandin endoperoxide synthase was subjected to the computer‐assisted homology search in the protein primary structure database, in order to investigate the regulation mechanism of the expression of prostaglandin endoperoxide synthase. As a result of that, it turned out that prostaglandin endoperoxide synthase shares sequence homology with ...
Toh, Hiroyuki, Hiroyuki Toh
openaire   +4 more sources

Stimulation of Transient Receptor Potential Channels TRPM3 and TRPM8 Increases Human Prostaglandin Endoperoxide Synthase-2 Promoter Activity. [PDF]

Molecules
The transient receptor potential channels TRPM3 and TRPM8 are cation channels that regulate numerous cellular activities, including thermo- and pain sensation.
Brandmeier N, Rössler OG, Thiel G.
europepmc   +3 more sources

Efectos renales de los inhibidores selectivos de la ciclooxigenasa-2 (COX-2) en la cirrosis. Estudios "in vivo" en ratas inducidas a cirrosis y estudios "in vitro" en células mesangiales. [PDF]

, 2006
[spa] En la cirrosis descompensada, la síntesis renal de prostaglandinas (PGs), juega un papel clave en el mantenimiento de la función renal. En concreto, las PGs renales contrarrestan la exacerbada actividad vasoconstrictora asociada a la activación de ...
López Parra, Marta
core   +6 more sources

The analysis of prostaglandin endoperoxide by high performance liquid chromatography and desorption chemical ionization mass spectrometry.

, 1989
The analysis of prostaglandin endoperoxide by high performance liquid chromatography and desorption chemical ionization mass ...
Alexander Bobak. Schilling (7965614)
core   +6 more sources

In situ imaging reveals disparity between prostaglandin localization and abundance of prostaglandin synthases

, 2021
Duncan et al. use a mass spectrometry imaging method to assess the localization and concentration of prostaglandins (PGs) in mouse tissues during pregnancy.
Erin S. Baker, Duncan, Kyle D.,, Sun, Xiaofei,, Baker, Erin S., Dey, Sudhansu K., Kyle D. Duncan, Baker, Erin S.,, Ingela Lanekoff, Duncan, Kyle D., Xiaofei Sun, Dey, Sudhansu K.,, Sudhansu K. Dey, Lanekoff, Ingela, Lanekoff, Ingela,, Sun, Xiaofei   +14 more
core   +1 more source

LC-MS/MS Confirms That COX-1 Drives Vascular Prostacyclin Whilst Gene Expression Pattern Reveals Non-Vascular Sites of COX-2 Expression [PDF]

, 2013
PMCID: PMC3711559This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are ...
Anna Nicolaou (261799), Warner, Timothy D., Louise S MacKenzie, Mitchell, JA, Nicolaou, A., Kirkby, NS, Anna Nicolaou, Jing Jiao (121723), Nicolaou, A, Urquhart, P, Zaiss, Anne K., Lundberg, Martina H., Nicolaou, Anna; id_orcid, Herschman, HR, Nicholas S. Kirkby (229832), Harvey R Herschman, Al-Yamani, Malak, Jane A Mitchell, Martina H Lundberg, Al-Yamani, M., Martina H. Lundberg (332728), Paula Urquhart, Malak Al-Yamani (432209), Mackenzie, Louise, Philip J Austin, Harvey R. Herschman (245626), Nicholas S Kirkby, Jiao, J, Herschman, H.R., Jing Jiao, Zaiss, A.K., Jiao, Jing, Kirkby, N.S., Warner, T.D., Anne K Zaiss, Lundberg, MH, MacKenzie, LS, Nicolaou, Anna, Austin, PJ, Timothy D Warner, Timothy D. Warner (200303), Philip J. Austin (432208), Al’Yamani, Malak, Urquhart, Paula, Anne K. Zaiss (432206), MacKenzie, Louise S., Urquhart, P., Lundberg, M.H., Louise S. MacKenzie (432210), Jiao, J., Paula Urquhart (432207), Mitchell, Jane A., Mitchell, J.A., Malak Al-Yamani, Mackenzie, Louise; id_orcid, Al-Yamani, M, Austin, Philip J., Herschman, Harvey R., MacKenzie, L.S., Zaiss, AK, Austin, P.J., Kirkby, Nicholas S., Jane A. Mitchell (128611), Warner, TD   +63 more
core   +2 more sources

Regulation of bone biology by prostaglandin endoperoxide H synthases (PGHS): A rose by any other name...

, 2006
It is well established that prostaglandins are essential mediators of bone resorption and formation. In the early 1990s, it was discovered that enzymatic reactions producing prostaglandins were regulated by two cyclooxygenase enzymes, one producing ...
Gregory, Laura S, Li, Li, Pettit, Allison, Forwood, Mark, Forwood, M. R., Gregory, Laura, Pettit, Allison R, Pettit, Allison R., Gregory, Laura S., Forwood, Mark R, Pettit, A. R., Gregory, L. S., Forwood, Mark R., Li, L.   +13 more
core   +1 more source

Unraveling the Mechanism of Xiaochaihu Granules in Alleviating Yeast-Induced Fever Based on Network Analysis and Experimental Validation

Pharmaceuticals
Xiaochaihu granules (XCHG) are extensively used to treat fever. Nevertheless, the underlying mechanism remains elusive. This study aimed to explore the potential of XCHG in mitigating yeast-induced fever and the underlying metabolic pathways.
Xiuli Chen, Hao Wu, Peibo Li, Wei Peng, Yonggang Wang, Xiaoli Zhang, Ao Zhang, Jinliang Li, Fenzhao Meng, Weiyue Wang, Weiwei Su   +10 more
doaj   +1 more source

Computational Studies on Functions and Reactions of Prostaglandin Synthases [PDF]

, 2018
研究成果の概要（和文）：本研究では、プロスタグランジン類の生合成を司る酵素の機能と反応について検討した。（１）プロスタグランジンH2合成酵素(シクロオキシゲナーゼ)：本研究では、シクロオキシゲナーゼ２型の酵素(COX-2)によるアラキドン酸の水素引き抜きの段階では、活性化エネルギーが、基質の立体配座に依存することをQM/MM法で明らかにした。（２）リポカリン型プロスタグランジンD合成酵素：プロスタグランジンD合成酵素の反応について検討し ...
MORI, Seiji, 森, 聖治
core   +3 more sources

Integrated O2 and H2 Gas Therapy via Microneedle‐Assisted Photocatalytic Water Splitting for Accelerating Diabetic Full‐Thickness Skin Wound Healing

Advanced Science, EarlyView.
A concept of integrated O2 and H2 gas therapy is achieved using a gas‐producing material. PMP nanoparticles, fabricated from platinum, MIL‐101(Fe)‐NH2, and phosphotungstic acid, are integrated into bilayer gelatin methacryloyl microneedles for transdermal delivery. These microneedles enable integrated O2 and H2 gas therapy and promote wound healing via
Zesheng Chen, Yanchao Yu, Xingyuan Xiao, Wenwen Cheng, Ye Yang, Zhengyao Zhang, Wang Wang, Zhijun Zhou, Weikang Hu, Xiaolong Wang, Bing Li, Kwang Leong Choy, Yun Chen, Zijian Wang   +13 more
wiley   +1 more source