Results 51 to 60 of about 69,164 (164)

Nitroarachidonic Acid, a Novel Peroxidase Inhibitor of Prostaglandin Endoperoxide H Synthases 1 and 2

, 2011
Prostaglandin endoperoxide H synthase (PGHS) catalyzes the oxidation of arachidonate to prostaglandin H2. We have previously synthesized and chemically characterized nitroarachidonic acid (AANO2), a novel anti-inflammatory signaling mediator. Herein, the
Valerie B. O'Donnell, Rubbo, H., Bonilla, L., Thomas, Christopher P., Marnett, L. J., Trostchansky, A., O'Donnell, Valerie Bridget, Lawrence J. Marnett, Rafael Radi, Christopher P. Thomas, Radi, R., Lucía Bonilla, Andrés Trostchansky, Homero Rubbo   +13 more
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Biochemical and pharmacological characterization of the cyclooxygenase activity of human blood prostaglandin endoperoxide synthases. J Pharmacol Exp Ther 271:1705–1712

, 1994
The aim of our study was to characterize a model of human prostaglandin endoperoxide synthase-
Anita Greco, P P, Paola Patrignani, Clara Natoli, Francesco Cipollone, M R P, Antonina Ganci, Carlo Patrono, A G, F C, Oncology, S L ), Stefano Iacobelli, Maria R Panara, C N, C P, O F, Ornella Fusco, Jacques Maclouf, Christophe Creminon   +19 more
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Ascorbic acid enhances the inhibitory effect of aspirin on neuronal cyclooxygenase-2-mediated prostaglandin E2 production. [PDF]

, 2006
Inhibition of neuronal cyclooxygenase-2 (COX-2) and hence prostaglandin E2 (PGE2) synthesis by non-steroidal anti-inflammatory drugs has been suggested to protect neuronal cells in a variety of pathophysiological situations including Alzheimer's disease ...
Akundi, Ravi Shankar, Candelario-Jalil, Eduardo, Munoz, Eduardo, Eduardo Muñoz, Michael Hüll, Lieb, Klaus, Klaus Lieb, Akundi, Ravi S., Ravi S. Akundi, Fiebich, Bernd L., Kurt Appel, Bhatia, Harsharan S., Eduardo Candelario-Jalil, Harsharan S. Bhatia, Hull, Michael, Bernd L. Fiebich, Appel, Kurt   +16 more
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Prostaglandin endoperoxide H synthase expression in human thyroid epithelial cells

, 2001
KAT-50, an established human thyrocyte cell line, expresses constitutively high levels of prostaglandin endoperoxide H synthase-2 (PGHS-2), the inflammatory cyclooxygenase. Here, we examine primary human thyrocytes. We find that they, too, express PGHS-2
H. James Cao, Andrew G. Gianoukakis, Timothy A. Jennings, Terry J. Smith   +3 more
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Potentiation Of Itch And Flare Responses In Human Skin By Prostaglandins E2 And H2 and A Prostaglandin Endoperoxide Analog [PDF]

, 1977
The itch and erythematous responses induced by intradermal injection of prostaglandin E2 (PGE2), the unstable prostaglandin endoperoxide PGH2 (t1/2 ∼ 5mm at 37°C) and the stable endoperoxide analog (15S)-hydroxy-9α 11α-(epoxymethano)prosta-5,13-dienoic ...
Strandberg, Kjell, Hägermark, Östen, Hamberg, Mats   +2 more
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Prostaglandin Endoperoxide H Synthases [PDF]

Journal of Biological Chemistry, 2007
Jiayan Liu, Steve A. Seibold, Caroline J. Rieke, Inseok Song, Robert I. Cukier, William L. Smith   +5 more
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Changes in the expression of prostaglandin E and F synthases at induced and spontaneous labour onset in the sheep

, 2004
The differential production of prostaglandin (PG) F(2 alpha) and PGE(2) within the uterine compartment may play a role in controlling myometrial contraction. We hypothesized that the enzymes downstream of PG endoperoxide synthase-2 (PGHS-2) determine the
Rice, G., Hirst, J. J., Ooi, G. T., Dellios, N. L., Palliser, H. K., Escalona, R. M., Young, I. R.   +6 more
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An investigation of the neuropharmacological and behavioural effects of fenamate and other NSAIDs. [PDF]

, 2001
Recent evidence has indicated that NSAIDs might have direct effects on CNS tissue in addition to their classical inhibitory action on COX enzymes. This thesis addresses this hypothesis using electrophysiological and behavioural techniques. The effects of
Foxon, Graham Ronald
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Characterization of signalling cross-talk between the EP2 and FP receptors in endometrial epithelial cells [PDF]

, 2009
Uterine fibroids are benign tumors that arise from the smooth-muscle uterine cells (myometrium) and are the most common uterine disorder occurring in as many as 30% of women over 35 years of age. Despite their frequent occurrence, the etiology of uterine
Abera, Aron Berhanie
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Prostaglandin Endoperoxide H Synthase-1 [PDF]

Journal of Biological Chemistry, 2001
Elizabeth D. Thuresson, Karen M. Lakkides, Caroline Jill Rieke, Ying Sun, Byron A. Wingerd, Renée Micielli, Anne M. Mulichak, Michael G. Malkowski, R. Michael Garavito, William L. Smith   +9 more
openaire   +1 more source