Results 1 to 10 of about 169 (165)
Studies on prostaglandin antagonists [PDF]
British Journal of Pharmacology, 1971 Summary Three prostaglandin antagonists have been examined for their ability to block PGE2 and PGF2α on human, guinea‐pig and isolated rat gastrointestinal muscle. 7‐oxa‐13‐Prostynoic acid was either a non‐selective antagonist, or was ineffective on the tissues studied; it had marked spasmogenic activity on the rat fundus.
A, Bennett, J, Posner
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Postepy higieny i medycyny doswiadczalnej, 1980 This study examined the antinociceptive effects of two prostaglandin antagonists, SC-25469 and SC-19220 in the rat. SC-25469 and SC-19220 inhibited acetic acid-induced writhing with ED50 s of 6.9 and 6.8 mg/kg p.o., respectively. When compared to other analgesics, the rank order of potency in the writhing test was morphine greater than pentazocine = U ...
R, Brus, J, Zabawska
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Inhibition of Hatching of Mouse Blastocysts in vitro by Prostaglandin Antagonists [PDF]
Biology of Reproduction, 1978 The escape of the blastocyst from the zona pellucida in vitro is probably the result of expansion due to fluid accumulation in the blastocoele. This fluid accumulation is mediated by the epithelial trophectoderm. Since prostagiandins of the E series are involved in the control of water movement across epithelia, the effect of prostaglandin antagonists ...
J D, Biggers +3 more
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Reduction of fertility of mice by the intrauterine injection of prostaglandin antagonists [PDF]
Reproduction, 1981 Summary. The intrauterine injection of 7-oxa-13-prostynoic acid, 18,18,20-trimethyl PGE-2, and meclofenamic acid in mice at the expected times of implantation significantly reduced the number of implantation sites. Indomethacin was ineffective possibly because it was exposed to high pH during the preparation of the solutions for ...
J D, Biggers +2 more
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Prostaglandins antagonistically control Bax activation during apoptosis [PDF]
Cell Death & Differentiation, 2010 The Bax protein (Bcl-2-associated X protein) is pivotal for the apoptotic process. Bax, which resides in an inactive form in the cytosol of healthy cells, is activated during the early stages of apoptosis and becomes associated with mitochondria through poorly understood mechanisms.
Lalier, Lisenn +7 more
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Intrahypothalamic Injections of Prostaglandins and Prostaglandin Antogonists and Feeding in Sheep
Journal of Dairy Science, 1974 Abstract Prostaglandins are thought to play a role in neural transmission, and we have considered the possibility that they may act as feedbacks from fat depots to the central nervous system for maintenance of energy balance. To test for direct prostaglandin effects on the hypothalamus, sheep were implanted with guides directed toward the hypothalamus.
C A, Baile +4 more
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Journal of Pharmacy and Pharmacology, 1990 Abstract Several polyphloretin phosphate (PPP) fractions (low mol. wt LC1259; high mol. wt LC1261; crude mixture, LC101) were confirmed in their established property as antagonists of the pharmacological actions of prostaglandins in a preparation of guinea-pig isolated ileum stimulated by prostaglandin (PG)E2. Further samples of the same
P B, Curtis-Prior +4 more
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Can an antagonist for prostaglandin receptor be an alternative of aspirin?
Folia Pharmacologica Japonica, 2016 openaire +3 more sources
Verapamil as a prostaglandin antagonist.
Indian journal of experimental biology, 1981 U N, Das, B V, Chainulu, S R, Naik
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[Antagonist of prostaglandin synthesis in the treatment of dysmenorrhea].
Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1979 openaire +1 more source