Results 21 to 30 of about 27,427 (303)
Cross-effect of TRPV1 and EP3 receptor on coughs and bronchopulmonary C-neural activities.
PLoS ONE, 2021 Prostaglandin E2 (PGE2)-induced coughs in vivo and vagal nerve depolarization in vitro are inhibited by systemic and local administration of prostaglandin EP3 receptor (L-798106) and TRPV1 antagonists (JNJ 17203212).
Xiuping Gao +4 more
doaj +1 more source
Frontiers in Immunology, 2022 Systemic lupus erythematosus is a complex autoimmune disease during which patients develop autoantibodies raised against nuclear antigens. During the course of the disease, by accumulating in secondary lymphoid organs (SLOs), basophils support ...
Christophe Pellefigues +9 more
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An enzyme that inactivates the inflammatory mediator leukotriene b4 restricts mycobacterial infection. [PDF]
PLoS ONE, 2013 While tuberculosis susceptibility has historically been ascribed to failed inflammation, it is now known that an excess of leukotriene A4 hydrolase (LTA4H), which catalyzes the final step in leukotriene B4 (LTB4) synthesis, produces a hyperinflammatory ...
David M Tobin +4 more
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Roles of EP Receptors in the Regulation of Fluid Balance and Blood Pressure
Frontiers in Endocrinology, 2022 Prostaglandin E2 (PGE2) is an important prostanoid expressing throughout the kidney and cardiovascular system. Despite the diverse effects on fluid metabolism and blood pressure, PGE2 is implicated in sustaining volume and hemodynamics homeostasis.
Lu Wang +12 more
doaj +1 more source
PPAR Research, 2014 Previous findings showed that the anticancer effects of combined γ-tocotrienol and peroxisome proliferator activated receptor γ (PPARγ) antagonist treatment caused a large reduction in PPARγ expression.
Abhita Malaviya, Paul W. Sylvester
doaj +1 more source
Indole-3-acetic Acid Antagonists of the Prostaglandin D2 Receptor CRTH2 [PDF]
, 2016 Prostaglandin D2 (PGD2) acting at the CRTH2 receptor (chemoattractant receptor-homologous molecule expressed on Th2 cells) has been linked with a variety of allergic and other inflammatory diseases.
Michael G. Hunter (2668429) +12 more
core +1 more source
Тіе Modern treatment of androgenetic alopecia
Vestnik Dermatologii i Venerologii, 2017 Androgenetic alopecia (AGA) is the most common reason for hair loss. Its frequency in Caucasian population is up to 80% in men and 42% in women. Current gold standard for AGA treatment includes minoxidil and/or finasteride.
V. K. Karnaukhov +4 more
doaj +1 more source
Indole-3-acetic acid antagonists of the prostaglandin D2 receptor CRTH2. [PDF]
, 2005 Prostaglandin D2 (PGD2) acting at the CRTH2 receptor (chemoattractant receptor-homologous molecule expressed on Th2 cells) has been linked with a variety of allergic and other inflammatory diseases.
Hay, PA +12 more
core +1 more source
Microglial inhibition of neuroprotection by antagonists of the EP1 prostaglandin E2 receptor
Journal of Neuroinflammation, 2009 Background The EP1 receptor for the prostanoid PGE2 is a G-protein coupled receptor that has been shown to contribute to excitotoxic neuronal death.
Rojas Monica A +6 more
doaj +1 more source
Eicosanoids in Cancer: Prostaglandin E2 Receptor 4 in Cancer Therapeutics and Immunotherapy
Frontiers in Pharmacology, 2020 The cyclooxygenase-2 (COX-2) enzyme is frequently overexpressed in epithelial malignancies including those of the breast, prostate, lung, kidney, ovary, and liver and elevated expression is associated with worse outcomes.
Mc Millan Ching +5 more
doaj +1 more source