Results 261 to 270 of about 258,151 (309)
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Prostate-Specific Antigen in Prostatic Cancer
American Journal of Clinical Oncology, 1988In an attempt to establish the value of prostate-specific antigen (PSA) in prostatic cancer, serum PSA measurements were performed in 600 patients, including 75 previously untreated prostatic cancer patients. The mean PSA levels in the benign prostatic hypertrophy (BPH) and cancer groups were highly significantly different, but less difference was ...
J C, Baron +5 more
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Urology, 1994
We attempt to correlate prebiopsy serum prostate-specific antigen (PSA) concentration and prostate-specific antigen density (PSAD) with histologic results of prostate biopsy.Sixty-two consecutive patients underwent prostate biopsy because of elevated PSA greater than 4 ng/mL and/or abnormal findings on digital rectal examination (DRE).
R, Bare, L, Hart, D L, McCullough
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We attempt to correlate prebiopsy serum prostate-specific antigen (PSA) concentration and prostate-specific antigen density (PSAD) with histologic results of prostate biopsy.Sixty-two consecutive patients underwent prostate biopsy because of elevated PSA greater than 4 ng/mL and/or abnormal findings on digital rectal examination (DRE).
R, Bare, L, Hart, D L, McCullough
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Journal of Urology, 2011 Purpose: Prostate specific antigen and free prostate specific antigen have limited specificity to detect clinically significant, curable prostate cancer, leading to unnecessary biopsy, and detection and treatment of some indolent tumors.
Alan W Partin +2 more
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New England Journal of Medicine, 1987
After half a century of clinical application, the usefulness of prostatic acid phosphatase (PAP) as a marker for carcinoma of the prostate is being challenged. Historically the first of the "serum markers" for the presence of a human cancer,1 acid phosphatase is still measured in clinical laboratories all over the world.
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After half a century of clinical application, the usefulness of prostatic acid phosphatase (PAP) as a marker for carcinoma of the prostate is being challenged. Historically the first of the "serum markers" for the presence of a human cancer,1 acid phosphatase is still measured in clinical laboratories all over the world.
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PROSTATE-SPECIFIC ANTIGEN DENSITY
Urologic Clinics of North America, 1997Nearly 20 years have passed since PSA was definitively identified. Throughout this period, its clinical application as a tumor marker has expanded significantly. Today, besides monitoring prostate cancer therapy, PSA is being used extensively in mass screening programs for early detection of adenocarcinoma of the prostate and has become the most ...
M C, Beduschi, J E, Oesterling
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The discovery of prostate‐specific antigen
BJU International, 2007The discovery of prostate‐specific antigen (PSA) was beset with controversy; as PSA is present in prostatic tissue and semen, it was independently discovered and given different names, thus adding to the controversy. In this review we document the early research in this field to describe the chronology of the discovery of PSA.
Amrith Raj, Rao +2 more
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Prostate-specific membrane antigen
The Prostate, 1997In an effort to discover new prostate-specific antigens (PSAs) to enhance our understanding of the functions and behavior of the prostate and the complex processes involved in prostate tumor progression, the structure and function of the PSM antigen has been elucidated.The PSM antigen was recognized using the 7E11-C5.3 monoclonal antibody, generated ...
W R, Fair, R S, Israeli, W D, Heston
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Prostate-Specific Antigen in Urine
European Urology, 1994We investigated concentrations of prostate-specific antigen (PSA) in mid-stream urine of 213 patients. Among them were 34 females. Diagnoses of the male patients were 42 benign prostatic hypertrophy (BPH), 21 localized prostate cancer prior to radical prostatectomy (RP), 15 post-RP without distant or local recurrence, 5 post-RP with local recurrence ...
J, Breul, U, Pickl, R, Hartung
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Prostatic Specific Antigen and Benign Prostatic Hyperplasia
Scandinavian Journal of Urology and Nephrology, 1996The aim of this study on patients (n = 51) with urodynamically proven obstruction was to search for correlations between serological levels of prostatic specific antigen (PSA) and age of patients, volume of prostate and prostatic morphology as evaluated on transurethral resection specimens.
Atan, ALİ +4 more
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1994
PSA is a 34-kDa 240-amino-acid glycoprotein produced exclusively by prostatic epithelial cells. PSA is a serine protease, is a member of the kallikrein gene family, and has a high sequence homology with human glandular kallikrein. It has chymotrypsin-, trypsin-, and esterase-like activities.
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PSA is a 34-kDa 240-amino-acid glycoprotein produced exclusively by prostatic epithelial cells. PSA is a serine protease, is a member of the kallikrein gene family, and has a high sequence homology with human glandular kallikrein. It has chymotrypsin-, trypsin-, and esterase-like activities.
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