Results 41 to 50 of about 645,171 (161)

Inhibitors of rhomboid proteases [PDF]

Biochimie, 2016
Rhomboid proteases form one of the most widespread families of intramembrane proteases. They utilize a catalytic serine-histidine dyad located several Å below the surface of the membrane for substrate hydrolysis. Multiple studies have implicated rhomboid proteases in biologically and medically relevant processes. Several assays have been developed that
Wolf, Eliane V., Verhelst, Steven
openaire   +3 more sources

Thermostable serine protease inhibitor from Death cap (Amanita phalloides)

Journal of Associated Medical Sciences, 2019
Background: Protease inhibitor plays an important role in many biological processes in an organism, its selective binding toward protease potentially tuning down some specific biological processes such as enzymatic catalysis regulation, protein signaling
phichaya khamai, Ketpaillin Chimong, Kritchai Pooncharoen, Widsanusan Chartarrayawadee   +3 more
doaj  

Carbohydrases are Digested by Proteases Present in Enzyme Preparations During in vitro Digestion

The Journal of Poultry Science, 2004
A protease present in an enzyme preparation may digest other enzymes and thus reduces the effectiveness of an enzyme preparation to improve digestibility of animal feeds.
Fuad Saleh, Akira Ohtsuka, Tsuneo Tanaka, Kunioki Hayashi   +3 more
doaj   +1 more source

Purification and Biochemical Characterization of a New Protease Inhibitor from Conyza dioscoridis with Antimicrobial, Antifungal and Cytotoxic Effects

Molecules, 2020
The main objective of the current study was the extraction, purification, and biochemical characterization of a protein protease inhibitor from Conyzadioscoridis. Antimicrobial potential and cytotoxic effects were also examined.
Aida Karray, Mona Alonazi, Slim Smaoui, Philippe Michaud, Dina Soliman, Abir Ben Bacha   +5 more
doaj   +1 more source

The Place of protease inhibitors in antiretroviral treatment

Brazilian Journal of Infectious Diseases
With the introduction of highly active antiretroviral therapy, a number of drugs have been developed. The best choice concerning which antiretroviral analogs to start is always under discussion, especially in the choice between non-nucleoside reverse ...
S.B. Tenore, P.R.A. Ferreira
doaj   +1 more source

Relation of postmortem protease activity to tenderness in buffalo meat and Brahman beef

Italian Journal of Animal Science, 2010
We previously showed that meat from crossbred water buffalo had significantly higher tenderness than beef from crossbred Brahman cattle of the same age, gender, and diet.
M. Hirabayashi, K. Chikuni, S. Muroya, T. Fujihara, L. C. Cruz, J.R. V. Herrera, R.M. Lapitan, A.N. Del Barrio, K.E. Neath, Y. Kanai   +9 more
doaj   +1 more source

Compensatory substitutions in the HCV NS3/4A protease cleavage sites are not observed in patients treated unsuccessfully with telaprevir combination treatment

Virology Journal, 2012
Background Development of compensatory mutations within the HIV p7/p1 and p1/p6 protease cleavage site region has been observed in HIV-infected patients treated with protease inhibitors.
Sullivan James C, Zhang Eileen Z, Bartels Doug J, Tigges Ann, Dorrian Jennifer L, Kwong Ann D, Kieffer Tara L   +6 more
doaj   +1 more source

Identification of covalent active site inhibitors of dengue virus protease

Drug Design, Development and Therapy, 2015
Xiaoying Koh-Stenta,1 Joma Joy,1 Si Fang Wang,1 Perlyn Zekui Kwek,1 John Liang Kuan Wee,1 Kah Fei Wan,2 Shovanlal Gayen,1 Angela Shuyi Chen,1 CongBao Kang,1 May Ann Lee,1 Anders Poulsen,1 Subhash G Vasudevan,3 Jeffrey Hill,1 Kassoum Nacro11Experimental ...
Koh-Stenta X, Joy J, Wang SF, Kwek PZ, Wee JLK, Wan KF, Gayen S, Chen AS, Kang C, Lee MA, Poulsen A, Vasudevan SG, Hill J, Nacro K   +13 more
doaj  

Phospholipid Binding Protein C Inhibitor (PCI) Is Present on Microparticles Generated In Vitro and In Vivo.

PLoS ONE, 2015
Protein C inhibitor is a secreted, non-specific serine protease inhibitor with broad protease reactivity. It binds glycosaminoglycans and anionic phospholipids, which can modulate its activity.
Katrin Einfinger, Sigrun Badrnya, Margareta Furtmüller, Daniela Handschuh, Herbert Lindner, Margarethe Geiger   +5 more
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Protease inhibitors

Journal of the Japanese Association for Infectious Diseases, 2005
YANG SYAULAN, WU JEN-DAR, SU FENG-YIH, KUO CHUN-WEI, CHEN WEN-CHANG, XIANG YIBIN, WANG CHING-CHENG, LIAO SHAO-YING   +7 more
openaire   +7 more sources