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Summary of Reivision of Law Concerning Protectin of Radiation Hazard
openaire +2 more sources
Correction for Gobbetti et al., Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection. [PDF]
europepmc +1 more source
Docosahexaenoic Acid and Its Metabolites Protect against Ozone-induced Pulmonary Inflammation. [PDF]
Yaeger MJ +22 more
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Intestinal flora composition and fecal metabolic phenotype in elderly patients with sleep disorders combined with type 2 diabetes. [PDF]
Yin Z +6 more
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Specialized Pro-Resolving Mediators as Emerging Players in Cardioprotection: From Inflammation Resolution to Therapeutic Potential. [PDF]
De Bartolo A +3 more
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There is currently a growing interest in docosahexaenoic acid (DHA) oxygenated metabolites. Among them, protectin D1 (PD1), an endogenous dihydroxylated and non-cyclic docosatriene made through lipoxygenation and hydrolysis of an epoxide intermediate, shows appealing biological effects.
Laurence Balas +2 more
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Total synthesis of the antiinflammatory and proresolving protectin D1
Tetrahedron Letters, 2011Stereoselective total synthesis of protectin D1 was completed through construction of the Z,E,E-triene structure by using the Suzuki coupling between the vinyl borane (C13–C22) and the vinyl iodide (C1–C12). The Z-enyne, the acetylene precursor of the vinyl borane was synthesized from optically active γ-TMS allylic alcohol in a straightforward way.
Narihito Ogawa, Yuichi Kobayashi
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