Results 191 to 200 of about 7,623,726 (294)

Assessing the in vitro Binding Affinity of Protein-RNA Interactions Using an RNA Pull-down Technique.

Bio Protoc, 2022
Chopra A, Balbous F, Biggar KK.
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Augmented prediction of multi-species protein-RNA interactions using evolutionary conservation of RNA-binding proteins. [PDF]

Nat Commun
He J, Zhou T, Hu LF, Jiao Y, Wang J, Yan S, Jia S, Chen Q, Zhu W, Zhang J, Jia M, Li Y, Wang X, Wang Y, Yang YT, Sun L.   +15 more
europepmc   +1 more source

Systematic comparison and prediction of the effects of missense mutations on protein-DNA and protein-RNA interactions. [PDF]

PLoS Comput Biol, 2021
Jiang Y, Liu HF, Liu R.
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

G-quadruplex structural motifs modulate protein-RNA interactions within the transcriptome. [PDF]

Genome Biol
Bhatt U, Evans CW, Cucchiarini A, Gros J, Iyer KS, Mergny JL, Smith NM.   +6 more
europepmc   +1 more source

Predicting dynamic cellular protein-RNA interactions by deep learning using in vivo RNA structures. [PDF]

Cell Res, 2021
Sun L, Xu K, Huang W, Yang YT, Li P, Tang L, Xiong T, Zhang QC.   +7 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Discovery and functional interrogation of SARS-CoV-2 protein-RNA interactions

, 2022
Yeo G, Xiang J, Mueller J, Luo E, Yee B, Schafer D, Schmok J, Tan F, Rothamel K, McVicar R, Kwong E, Croker B, Jones K, Her H, Chen C, Vu A, Jin W, Park S, Le P, Brennan K, Kofman E, Li Y, Tankka A, Dong K, Song Y, Clark A, Carlin A, Nostrand EV, Leibel S.   +28 more
europepmc   +2 more sources

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source