Results 201 to 210 of about 7,623,726 (294)

Sequence-encoded and composition-dependent protein-RNA interactions control multiphasic condensate morphologies. [PDF]

Nat Commun, 2021
Kaur T, Raju M, Alshareedah I, Davis RB, Potoyan DA, Banerjee PR.   +5 more
europepmc   +1 more source

diPaRIS: Dynamic and Interpretable Protein-RNA Interactions Prediction With U-Shaped Network and Novel Structure Encoding. [PDF]

Adv Sci (Weinh)
Zhang L, Lu C, Peng X, Guo F, Li H, Wang J.   +5 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Protein-RNA interactions mediated by silvestrol-insight into a unique molecular clamp. [PDF]

Nucleic Acids Res
Naineni SK, Bhatt G, Jiramongkolsiri E, Robert F, Cencic R, Huang S, Nagar B, Pelletier J.   +7 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Rapidly Growing Protein-Centric Technologies to Extensively Identify Protein-RNA Interactions: Application to the Analysis of Co-Transcriptional RNA Processing. [PDF]

Int J Mol Sci, 2021
Masuda A, Kawachi T, Ohno K.
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Decoding protein-RNA interactions using CLIP-based methodologies. [PDF]

Nat Rev Genet
Xiang JS, Schafer DM, Rothamel KL, Yeo GW.   +3 more
europepmc   +1 more source

PremPRI: Predicting the Effects of Missense Mutations on Protein-RNA Interactions. [PDF]

Int J Mol Sci, 2020
Zhang N, Lu H, Chen Y, Zhu Z, Yang Q, Wang S, Li M.   +6 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source