Results 141 to 150 of about 32,649 (220)
Artificial lipidation of proteins and peptides: from mechanism to clinical applications
The FEBS Journal, Volume 293, Issue 5, Page 1269-1284, March 2026.Artificial lipidation transforms protein and peptide therapeutics by attaching fatty acid chains through reversible or permanent chemical strategies. This biomimetic approach delivers four key therapeutic advantages: extended circulation times (enabling weekly instead of daily dosing), alternative administration routes including oral delivery, precise ...
Jiaming Mu, Emily Vong, Sheiliza Carmali
wiley +1 more source
Hesperidin Encapsulation for Food, Pharmaceutical, and Chemical Industries: A Bibliometric Review
Journal of Food Process Engineering, Volume 49, Issue 3, March 2026.The encapsulation of hesperidin in solid matrices is an excellent strategy for overcoming pharmacokinetic limitations while maintaining its antioxidant, antidiabetic, anti‐inflammatory, and neuroprotective properties. This study highlights the multidisciplinary scope of the research as well as the versatility of encapsulated hesperidin in the ...
Thais Fernanda de Marco +3 more
wiley +1 more source
Heterogeneity of iridoid biosynthesis in catmints: Molecular background in a phylogenetic context
Journal of Integrative Plant Biology, Volume 68, Issue 3, Page 694-718, March 2026.Evolutionary gains and losses of key biosynthetic genes likely resulting from multiple independent evolutionary events explain why certain Nepeta (catnip) species produce both the active, cat‐attracting nepetalactones and sugar‐bound iridoids, while others make only the sugar‐bound forms, and some have lost iridoid production entirely.
Tijana Banjanac +15 more
wiley +1 more source
Acyl carrier protein. IX. Acyl carrier protein hydrolase.
The Journal of biological chemistry, 1967 P R, Vagelos, A R, Larrabes
openaire +1 more source
New Phytologist, Volume 249, Issue 5, Page 2196-2214, March 2026.Summary Plant‐derived oils are essential sources of reduced carbon and various fatty acid (FA) structures for food, biofuels, and the oleochemical industry. Despite extensive efforts, engineering mainstream oilseed crops to produce high levels of industrially valuable unusual FAs (UFAs) remains challenging.
Prasad Parchuri +4 more
wiley +1 more source
Disruption of Hepatic Insulin Signaling Causes Phospholipid Dysregulation in Mice
The FASEB Journal, Volume 40, Issue 4, 28 February 2026.Pan et al. demonstrate that disruption of hepatic insulin signaling by insulin receptor (IR) substrate (IRS1/2) deletion led to impaired PI3K‐AKT signaling, causing increased Foxo1 activation and TGF‐β1 expression, which dysregulated the expression of the key enzymes involving phospholipid biosynthesis and remodeling.
Quan Pan +6 more
wiley +1 more source
Acyl carrier protein. X. Acyl carrier protein synthetase.
The Journal of biological chemistry, 1968 J, Elovson, P R, Vagelos
openaire +1 more source
Gram‐Scale Synthesis of an Arylsulfonamide‐Type Alkaline Phosphatase Inhibitor
ChemMedChem, Volume 21, Issue 4, 25 February 2026.A larger amount of a tissue‐nonspecific alkaline phosphatase inhibitor, 5‐((5‐chloro‐2‐methoxyphenyl)sulfonamido)nicotinamide, was synthesized in five steps using a parallel method without the need for chromatography or crystallization. Because a single batch was used for in vivo studies in a large population of mice, the pharmacological results were ...
Zsolt Rapi +2 more
wiley +1 more source