Results 31 to 40 of about 32,649 (220)

Fatty acid acylation of proteins: specific roles for palmitic, myristic and caprylic acids

Oilseeds and fats, crops and lipids, 2016
Fatty acid acylation of proteins corresponds to the co- or post-translational covalent linkage of an acyl-CoA, derived from a fatty acid, to an amino-acid residue of the substrate protein.
Rioux Vincent
doaj   +1 more source

Assaying protein palmitoylation in plants

Plant Methods, 2008
Background Protein S-acylation (also known as palmitoylation) is the reversible post-translational addition of acyl lipids to cysteine residues in proteins through a thioester bond. It allows strong association with membranes.
Taylor Laura, Hemsley Piers A, Grierson Claire S   +2 more
doaj   +1 more source

Preparation of Affinity Purified Antibodies against ε-Glutaryl-Lysine Residues in Proteins for Investigation of Glutarylated Proteins in Animal Tissues

Biomolecules, 2021
The glutarylation of lysine residues in proteins attracts attention as a possible mechanism of metabolic regulation, perturbed in pathologies. The visualization of protein glutarylation by antibodies specific to ε-glutaryl-lysine residues may be ...
Artem V. Artiukhov, Ekaterina F. Kolesanova, Aleksandra I. Boyko, Anastasiya A. Chashnikova, Sergei N. Gnedoy, Thilo Kaehne, Daria A. Ivanova, Alyona V. Kolesnichenko, Vasily A. Aleshin, Victoria I. Bunik   +9 more
doaj   +1 more source

Dynamic Characterization of Protein and Posttranslational Modification Levels in Mycobacterial Cholesterol Catabolism

mSystems, 2020
Cholesterol of the host macrophage membrane is vital for mycobacterial infection, replication, and persistence. During chronic infection within host lung tissues, cholesterol facilitates the phagocytosis of mycobacteria into macrophages.
Jun-Yu Xu, Lei Zhao, Ying Xu, Bolin Li, Linhui Zhai, Minjia Tan, Bang-Ce Ye   +6 more
doaj   +3 more sources

Analysis of Protein Acylation

Current Protocols in Protein Science, 2009
AbstractProteins can be acylated with a variety of fatty acids attached by different covalent bonds, influencing, among other things, their function and intracellular localization. This unit describes methods to analyze protein acylation, both levels of acylation and also the identification of the fatty acid and the type of bond present in the protein ...
Zeidman, R, Jackson, CS, Magee, AI
openaire   +4 more sources

Coenzyme A binding sites induce proximal acylation across protein families

Scientific Reports, 2023
Lysine Nɛ-acylations, such as acetylation or succinylation, are post-translational modifications that regulate protein function. In mitochondria, lysine acylation is predominantly non-enzymatic, and only a specific subset of the proteome is acylated ...
Chris Carrico, Andrew Cruz, Marius Walter, Jesse Meyer, Cameron Wehrfritz, Samah Shah, Lei Wei, Birgit Schilling, Eric Verdin   +8 more
doaj   +1 more source

Acylation of HIV proteins

Biochemical Society Transactions, 1989
info:eu-repo/semantics ...
Saermark, T, Bex, Françoise
openaire   +3 more sources

2-Acylglycerolphosphoethanolamine acyltransferase/acyl-acyl carrier protein synthetase is a membrane-associated acyl carrier protein binding protein

Journal of Biological Chemistry, 1989
Two enzymatic activities, 2-acylglycerolphosphoethanolamine (2-acyl-GPE) acyltransferase and acyl-acyl carrier protein (acyl-ACP) synthetase, were solubilized and purified from Escherichia coli membranes. Electrophoretic analysis of the final product of the purification procedure revealed a single protein species with an apparent molecular mass of 27 ...
C L, Cooper, L, Hsu, S, Jackowski, C O, Rock   +3 more
openaire   +2 more sources

GCP16 stabilizes the DHHC9 subfamily of protein acyltransferases through a conserved C-terminal cysteine motif

Frontiers in Physiology, 2023
Protein S-acylation is a reversible lipid post-translational modification that allows dynamic regulation of processes such as protein stability, membrane association, and localization.
Phillip L. Nguyen, Wendy K. Greentree, Toshimitsu Kawate, Maurine E. Linder   +3 more
doaj   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source