Identification of Novel Plasma Biomarkers for Abdominal Aortic Aneurysm by Protein Array Analysis [PDF]
Biomolecules, 2022 Abdominal aortic aneurysm (AAA) is a potentially life-threatening disease that is common in the aging population. Currently, there are no approved diagnostic biomarkers or therapeutic drugs for AAA.
Jianqiang Wu +13 more
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Protein and Peptide Array Analysis of Autoimmune Disease [PDF]
BioTechniques, 2002 Molecular cloning, sequencing of the human genome, and other major advances in biomedical research have contributed substantially to our understanding of autoimmune disease.
William H. Robinson +2 more
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Reverse-phase protein array analysis to identify biomarker proteins in human pancreatic cancer. [PDF]
Dig Dis Sci, 2014 Pancreatic cancer is the fourth leading cause of cancer death in the United States. The high mortality rate of patients with pancreatic cancer is primarily due to the difficulty of early diagnosis and a lack of effective therapies. There is an urgent need to discover novel molecular targets for early diagnosis and new therapeutic approaches to improve ...
Huang YJ +4 more
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CF-PPiD technology based on cell-free protein array and proximity biotinylation enzyme for in vitro direct interactome analysis [PDF]
Scientific Reports, 2022 Protein–protein interaction (PPI) analysis is a key process to understand protein functions. Recently, we constructed a human protein array (20 K human protein beads array) consisting of 19,712 recombinant human proteins produced by a wheat cell-free ...
Shusei Sugiyama +6 more
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Urinary Protein Array Analysis to Identify Key Inflammatory Markers in Children with IgA Vasculitis Nephritis [PDF]
Children, 2022 Chronic kidney disease is a recognised complication of immunoglobulin A vasculitis, (IgAV; formerly Henoch–Schonlein purpura—HSP). The pathophysiology of IgAV and why some patients develop significant renal involvement remains largely unknown ...
Julien Marro +4 more
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Rare osteosarcoma cell subpopulation protein array and profiling using imaging mass cytometry and bioinformatics analysis [PDF]
BMC Cancer, 2020 Background Single rare cell characterization represents a new scientific front in personalized therapy. Imaging mass cytometry (IMC) may be able to address all these questions by combining the power of MS-CyTOF and microscopy.
Izhar S. Batth +7 more
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Discovery of crucial cytokines associated with deep vein thrombus formation by protein array analysis [PDF]
BMC Cardiovascular DisordersBackground Expanding the number of biomarkers is imperative for studying the etiology and improving venous thromboembolism prediction. In this study, we aimed to identify promising biomarkers or targeted therapies to improve the detection accuracy of ...
Qitao Wang +6 more
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Novel computational analysis of protein binding array data identifies direct targets of
BMC Bioinformatics, 2011 Background The creation of a complete genome-wide map of transcription factor binding sites is essential for understanding gene regulatory networks in vivo.
Kaestner Klaus H +4 more
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Proteomic applications of surface plasmon resonance biosensors: analysis of protein arrays [PDF]
Experimental & Molecular Medicine, 2005 Proteomics is one of the most important issues in the post-genomic area, because it can greatly contribute to identifying protein biomarkers for disease diagnosis and drug screening. Protein array is a key technology for proteome researches and has been analyzed by various methods including fluorescence, mass spectrometry, atomic force microscopy and ...
Jong Seol Yuk, Kwon‐Soo Ha
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A Network-based Analysis of Polyanion-binding Proteins Utilizing Human Protein Arrays [PDF]
Journal of Biological Chemistry, 2007 The existence of interactions between many cellular proteins and various polyanionic surfaces within a cell is now well established. The functional role of such interactions, however, remains to be clearly defined. The existence of protein arrays, with a large selection of different kinds of proteins, provides a way to better address a number of ...
Nazila Salamat‐Miller +5 more
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