Results 101 to 110 of about 25,768,908 (251)

Tick lipocalin triggers mammalian IGFBP-3-mediated apoptosis in macrophages and keratinocytes

Frontiers in Immunology
Ticks secrete several molecules, including lipocalins, in their saliva during blood feeding on a vertebrate host. In this study, we provide novel evidence on the role of Ornithodoros turicata americanus tick lipocalin (Otlip) in modulating cytokine ...
Krittika Nandy, P. P. Mahesh, Lichao Liu, Daniel E. Sonenshine, Daniel E. Sonenshine, Hameeda Sultana, Girish Neelakanta   +6 more
doaj   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

Capillary electrophoresis coupled to fluorescence spectroscopy for protein characterisation [PDF]

, 2012
Proteins are essential molecules in all living organisms. Their involvement in numerous biological processes has led to the development of protein-based medicines (biopharmaceuticals).
Sub Biomolecular analysis, de Kort, B.J., Biomolecular Analysis   +2 more
core   +1 more source

Copine‐4 Paraneoplastic Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We characterize copine‐4 (CPNE4)‐IgG and report clinical associations. Among 844 samples with unclassified neural IgGs identified by mouse‐brain indirect immunofluorescence assay over 2 years, 5 samples (serum, 3; CSF, 2) from 3 patients produced a distinctive cerebrum‐restricted synaptic pattern.
Mimi S. Fang, Amy Ml Quek, Clement Yong, Amir Adeli, Gabrielle N. Conway, Connie E. Lesnick, Diana Anissian, Divyanshu Dubey, John R. Mills, Sean J. Pittock, Anastasia Zekeridou, Michael Gilligan, Andrew McKeon   +12 more
wiley   +1 more source

Chemical-genetic profile analysis in yeast suggests that a previously uncharacterized open reading frame, YBR261C, affects protein synthesis

BMC Genomics, 2008
Background Functional genomics has received considerable attention in the post-genomic era, as it aims to identify function(s) for different genes. One way to study gene function is to investigate the alterations in the responses of deletion mutants to ...
Eroukova Veronika, Alamgir Md, Jessulat Matthew, Xu Jianhua, Golshani Ashkan   +4 more
doaj   +1 more source

Bio‐Inspired Artificial Ionic Mechanoreceptor

Advanced Functional Materials, EarlyView.
A skin‐inspired artificial mechanoreceptor based on ionic interactions is presented for biomimetic tactile sensing. Pressure‐driven ionic redistribution within microfluidic channels generates a self‐powered electrical signal without external bias. The generated waveform exhibits mechanoreceptor‐like temporal features, including overshoot and undershoot,
Mohammad Akbari, Jeppe Don, Lasse A. N. Pedersen, John Noee, Rassoul Tabassian   +4 more
wiley   +1 more source

Enhancing protein-protein docking by new approaches to protein flexibility and scoring of docking hypotheses [PDF]

, 2004
Zöllner FG. Enhancing protein-protein docking by new approaches to protein flexibility and scoring of docking hypotheses. Bielefeld (Germany): Bielefeld University; 2004.Für das Verständnis von biologischen Funktionen können Proteindockingverfahren ...
Frank G. Zöllner, Zöllner, Frank Gerrit   +1 more
core  

Combined Oligonucleotide and Protein Microarray Temporal Analysis of p53-mediated Apoptosis

, 2005
Background: P53-mediated apoptosis involves a complex process induced largely by p53 acting as a transcription factor. We hypothesised that p53 expression would lead to transcriptional events that rapidly change during apoptosis and that protein array ...
Bailey A., Wee E., Lambe T., Ogg G.S., Jones L., Black A.P.   +5 more
core   +4 more sources

Configurable 3D-integrated focal-plane sensor-processor array architecture [PDF]

, 2008
A mixed-signal Cellular Visual Microprocessor architecture with digital processors is described. An ASIC implementation is also demonstrated. The architecture is composed of a regular sensor readout circuit array, prepared for 3D face-to-face type ...
Rekeczky, Csaba, Földesy, Péter, Zarándy, Ákos   +2 more
core   +1 more source

Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7

BMC Genomics, 2008
Background Protein kinases and phosphatases regulate protein phosphorylation, a critical means of modulating protein function, stability and localization.
Neszt Michael, Zadworny Megan, Por Hanting, Knockleby James, Szapiel Nicolas, Nguyen Thao, Logan Michael R, Harrison Paul, Bussey Howard, Mandato Craig A, Vogel Jackie, Lesage Guillaume   +11 more
doaj   +1 more source