Results 11 to 20 of about 559,282 (295)

Analysis of protein interaction and function with a 3-dimensional MALDI-MS protein array [PDF]

open access: yesBioTechniques, 2005
Protein profiling and characterization of protein interactions in biological samples ultimately require indicator-free methods of signal detection, which likewise offer an opportunity to distinguish specific interactions from nonspecific protein binding.
Igor M. Gavin   +4 more
doaj   +3 more sources

Tick lipocalin triggers mammalian IGFBP-3-mediated apoptosis in macrophages and keratinocytes [PDF]

open access: yesFrontiers in Immunology
Ticks secrete several molecules, including lipocalins, in their saliva during blood feeding on a vertebrate host. In this study, we provide novel evidence on the role of Ornithodoros turicata americanus tick lipocalin (Otlip) in modulating cytokine ...
Krittika Nandy   +6 more
doaj   +2 more sources

A Label-Free Fluorescent Array Sensor Utilizing Liposome Encapsulating Calcein for Discriminating Target Proteins by Principal Component Analysis [PDF]

open access: goldSensors, 2017
A new fluorescent arrayed biosensor has been developed to discriminate species and concentrations of target proteins by using plural different phospholipid liposome species encapsulating fluorescent molecules, utilizing differences in permeation of the ...
Ryota Imamura   +5 more
doaj   +2 more sources

RPPanalyzer Toolbox: An improved R package for analysis of reverse phase protein array data

open access: goldBioTechniques, 2014
Analysis of large-scale proteomic data sets requires specialized software tools, tailored toward the requirements of individual approaches. Here we introduce an extension of an open-source software solution for analyzing reverse phase protein array (RPPA)
Silvia von der Heyde   +8 more
doaj   +2 more sources

Protein Array Based Interactome Analysis of Amyloid-β Indicates an Inhibition of Protein Translation

open access: greenJournal of Proteome Research, 2011
Oligomeric amyloid-β is currently of interest in amyloid-β mediated toxicity and the pathogenesis of Alzheimer's disease. Mapping the amyloid-β interaction partners could help to discover novel pathways in disease pathogenesis. To discover the amyloid-β interaction partners, we applied a protein array with more than 8100 unique recombinantly expressed ...
Dezső P. Virók   +9 more
openalex   +4 more sources

Data in support of proteomic analysis of pneumococcal pediatric clinical isolates to construct a protein array

open access: goldData in Brief, 2016
Surface proteins play key roles in the interaction between cells and their environment, and in pathogenic microorganisms they are the best targets for drug or vaccine discovery and/or development.
Alfonso Olaya-Abril   +2 more
doaj   +2 more sources

Protein Expression of Cyclin B1, Transferrin Receptor, and Fibronectin Is Correlated with the Prognosis of Adrenal Cortical Carcinoma [PDF]

open access: yesEndocrinology and Metabolism, 2020
BackgroundAdrenal cortical carcinoma (ACC) is a rare cancer with a variable prognosis. Several prognostic factors of ACC have been previously reported, but a proteomic analysis has not yet been performed.
Sun Joon Moon   +3 more
doaj   +1 more source

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