Analysis of protein interaction and function with a 3-dimensional MALDI-MS protein array [PDF]
Protein profiling and characterization of protein interactions in biological samples ultimately require indicator-free methods of signal detection, which likewise offer an opportunity to distinguish specific interactions from nonspecific protein binding.
Igor M. Gavin +4 more
doaj +3 more sources
Tick lipocalin triggers mammalian IGFBP-3-mediated apoptosis in macrophages and keratinocytes [PDF]
Ticks secrete several molecules, including lipocalins, in their saliva during blood feeding on a vertebrate host. In this study, we provide novel evidence on the role of Ornithodoros turicata americanus tick lipocalin (Otlip) in modulating cytokine ...
Krittika Nandy +6 more
doaj +2 more sources
A Label-Free Fluorescent Array Sensor Utilizing Liposome Encapsulating Calcein for Discriminating Target Proteins by Principal Component Analysis [PDF]
A new fluorescent arrayed biosensor has been developed to discriminate species and concentrations of target proteins by using plural different phospholipid liposome species encapsulating fluorescent molecules, utilizing differences in permeation of the ...
Ryota Imamura +5 more
doaj +2 more sources
RPPanalyzer Toolbox: An improved R package for analysis of reverse phase protein array data
Analysis of large-scale proteomic data sets requires specialized software tools, tailored toward the requirements of individual approaches. Here we introduce an extension of an open-source software solution for analyzing reverse phase protein array (RPPA)
Silvia von der Heyde +8 more
doaj +2 more sources
Efficiency of Disease and Disease Activity Diagnosis Models of Systemic Lupus Erythematosus Based on Protein Array Analysis. [PDF]
Zhao Y, Qi Y, Liu X, Cui Y, Zhao Z.
europepmc +3 more sources
Protein Array Based Interactome Analysis of Amyloid-β Indicates an Inhibition of Protein Translation
Oligomeric amyloid-β is currently of interest in amyloid-β mediated toxicity and the pathogenesis of Alzheimer's disease. Mapping the amyloid-β interaction partners could help to discover novel pathways in disease pathogenesis. To discover the amyloid-β interaction partners, we applied a protein array with more than 8100 unique recombinantly expressed ...
Dezső P. Virók +9 more
openalex +4 more sources
Surface proteins play key roles in the interaction between cells and their environment, and in pathogenic microorganisms they are the best targets for drug or vaccine discovery and/or development.
Alfonso Olaya-Abril +2 more
doaj +2 more sources
HalolinkTM protein arrays for the functional analysis of proteins
Comunicaciones a ...
Patricia A. Bresnahan
openalex +3 more sources
Discovery of crucial cytokines associated with abdominal aortic aneurysm formation by protein array analysis. [PDF]
Li Y +6 more
europepmc +3 more sources
Protein Expression of Cyclin B1, Transferrin Receptor, and Fibronectin Is Correlated with the Prognosis of Adrenal Cortical Carcinoma [PDF]
BackgroundAdrenal cortical carcinoma (ACC) is a rare cancer with a variable prognosis. Several prognostic factors of ACC have been previously reported, but a proteomic analysis has not yet been performed.
Sun Joon Moon +3 more
doaj +1 more source

