Results 21 to 30 of about 927,101 (310)

Protein Expression of Cyclin B1, Transferrin Receptor, and Fibronectin Is Correlated with the Prognosis of Adrenal Cortical Carcinoma [PDF]

open access: yesEndocrinology and Metabolism, 2020
BackgroundAdrenal cortical carcinoma (ACC) is a rare cancer with a variable prognosis. Several prognostic factors of ACC have been previously reported, but a proteomic analysis has not yet been performed.
Sun Joon Moon   +3 more
doaj   +1 more source

Identification of Novel Plasma Biomarkers for Abdominal Aortic Aneurysm by Protein Array Analysis

open access: yesBiomolecules, 2022
Abdominal aortic aneurysm (AAA) is a potentially life-threatening disease that is common in the aging population. Currently, there are no approved diagnostic biomarkers or therapeutic drugs for AAA.
Jianqiang Wu   +13 more
doaj   +1 more source

Sodium danshensu attenuates cerebral ischemia–reperfusion injury by targeting AKT1

open access: yesFrontiers in Pharmacology, 2022
The beneficial properties of Sodium Danshensu (SDSS) for controlling cerebral ischemia and reperfusion injury (CIRI) are elucidated here both in vivo and in vitro.
Qing Gao   +10 more
doaj   +1 more source

Systematic identification of the interventional mechanism of Qingfei Xiaoyan Wan (QFXYW) in treatment of the cytokine storm in acute lung injury using transcriptomics-based system pharmacological analyses

open access: yesPharmaceutical Biology, 2022
Context Acute lung injury (ALI) is a complex, severe inflammation disease with high mortality, and there is no specific and effective treatment for ALI.
Jing-Yi Hou   +7 more
doaj   +1 more source

An Automated Approach to Assess Relative Galectin-Glycan Affinity Following Glycan Microarray Analysis

open access: yesFrontiers in Molecular Biosciences, 2022
Numerous studies have highlighted the utility of glycan microarray analysis for the elucidation of protein-glycan interactions. However, most current glycan microarray studies analyze glycan binding protein (GBP)-glycan interactions at a single protein ...
Alex D. Ho   +6 more
doaj   +1 more source

RPPanalyzer: Analysis of reverse-phase protein array data [PDF]

open access: yesBioinformatics, 2010
Abstract Summary: RPPanalyzer is a statistical tool developed to read reverse-phase protein array data, to perform the basic data analysis and to visualize the resulting biological information. The R-package provides different functions to compare protein expression levels of different samples and to normalize the data.
Mannsperger, Heiko A.   +4 more
openaire   +4 more sources

CF-PPiD technology based on cell-free protein array and proximity biotinylation enzyme for in vitro direct interactome analysis

open access: yesScientific Reports, 2022
Protein–protein interaction (PPI) analysis is a key process to understand protein functions. Recently, we constructed a human protein array (20 K human protein beads array) consisting of 19,712 recombinant human proteins produced by a wheat cell-free ...
Shusei Sugiyama   +6 more
doaj   +1 more source

High-throughput analysis and protein engineering using microcapillary arrays [PDF]

open access: yesNature Chemical Biology, 2015
We describe a multipurpose technology platform, termed μSCALE (microcapillary single-cell analysis and laser extraction), that enables massively parallel, quantitative biochemical and biophysical measurements on millions of protein variants expressed from yeast or bacteria.
Bob Chen   +8 more
openaire   +3 more sources

Pro-MAP: a robust pipeline for the pre-processing of single channel protein microarray data

open access: yesBMC Bioinformatics, 2022
Background The central role of proteins in diseases has made them increasingly attractive as therapeutic targets and indicators of cellular processes. Protein microarrays are emerging as an important means of characterising protein activity.
Metoboroghene Oluwaseyi Mowoe   +6 more
doaj   +1 more source

Application of mRNA Arrays for the Production of mCherry Reporter-Protein Arrays for Quantitative Gene Expression Analysis [PDF]

open access: yesACS Synthetic Biology, 2019
The development of programmable regulators that precisely and predictably control gene expression is a major goal of synthetic biology. Consequently, rapid high-throughput biochemical methods capable of quantitatively analyzing all components of gene expression would be of value in the characterization and optimization of regulator performance. In this
Masoud Norouzi   +4 more
openaire   +4 more sources

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