Results 31 to 40 of about 927,101 (310)

Profiling of Measles-Specific Humoral Immunity in Individuals Following Two Doses of MMR Vaccine Using Proteome Microarrays

Viruses, 2015
Introduction: Comprehensive evaluation of measles-specific humoral immunity after vaccination is important for determining new and/or additional correlates of vaccine immunogenicity and efficacy.
Iana H. Haralambieva, Whitney L. Simon, Richard B. Kennedy, Inna G. Ovsyannikova, Nathaniel D. Warner, Diane E. Grill, Gregory A. Poland   +6 more
doaj   +1 more source

Analyzing the Impact of Diesel Exhaust Particles on Lung Fibrosis Using Dual PCR Array and Proteomics: YWHAZ Signaling

Toxics, 2023
Air pollutants are associated with exacerbations of asthma, chronic bronchitis, and airway inflammation. Diesel exhaust particles (DEPs) can induce and worsen lung diseases.
Byeong-Gon Kim, Pureun-Haneul Lee, Jisu Hong, An-Soo Jang   +3 more
doaj   +1 more source

Genome Network Project: An Integrated Genomic Platform [PDF]

, 2009
With the objective of elucidating the structure of gene interactions in the human genome, the Genome Network Project has generated a vast quantity of experimental data, mainly focusing on transcriptional control and transcription-factor related protein ...
Jose C. Clemente, Kazuho Ikeo, So Nakagawa, Takashi Gojobori   +3 more
core   +2 more sources

Membrane Array Analysis of Tear Proteins in Ocular Cicatricial Pemphigoid [PDF]

Optometry and Vision Science, 2011
To explore non-invasive, protein-based, membrane array technology as a means to evaluate the global immune and angiogenic profile of tear proteins in patients with active ocular cicatricial pemphigoid (OCP).Forty-three proteins consisting of cytokines, angiogenic/growth factors, and immunoinflammatory modulators were measured by membrane array in tear ...
Matilda F. Chan, David A. Quigley, Erich C. Strauss, Douglas S. Holsclaw, Shimin Li, Nancy A. McNamara, Sonal Sathe, Robert A. Sack, Trinka Vijmasi   +8 more
openaire   +2 more sources

Analysis of patients with colorectal cancer shows a specific increase in serum anti-ING1 autoantibody levels

BMC Cancer, 2023
Colorectal cancer (CRC) is the third most prevalent cancer in the world, yet the sensitivity and specificity of biomarkers for CRC diagnosis are insufficient.
Takahiro Arasawa, Takaki Hiwasa, Akiko Kagaya, Tetsuro Maruyama, Masaya Uesato, Masayuki Kano, Sohei Kobayashi, Hirotaka Takizawa, Katsuro Iwase, Fumio Nomura, Kazuyuki Matsushita, Hisahiro Matsubara   +11 more
doaj   +1 more source

The Regulatory Role of MeAIB in Protein Metabolism and the mTOR Signaling Pathway in Porcine Enterocytes. [PDF]

, 2018
Amino acid transporters play an important role in cell growth and metabolism. MeAIB, a transporter-selective substrate, often represses the adaptive regulation of sodium-coupled neutral amino acid transporter 2 (SNAT2), which may act as a receptor and ...
Ji, Peng, Li, Guangran, Li, Jianjun, Tan, Bie, Tang, Yulong, Yin, Yulong   +5 more
core   +2 more sources

A targeted antibody-based array reveals a serum protein signature as biomarker for adolescent idiopathic scoliosis patients

BMC Genomics, 2023
Background Evident adolescent idiopathic scoliosis (AIS) incurs high treatment costs, low quality of life, and many complications. Early screening of AIS is essential to avoid progressing to an evident stage.
Zhenxuan Shao, Zengjie Zhang, Yiting Tu, Chongan Huang, Liang Chen, Anna Sun, Sunren Sheng, Xiaolei Zhang, Yan Wu   +8 more
doaj   +1 more source

NLRP3 monomer Functional Dynamics: from the Effects of Allosteric Binding to Implications for Drug Design [PDF]

International Journal of Biological Macromolecules 246 (2023) 125609, 2023
The protein NLRP3 and its complexes are associated with an array of inflammatory pathologies, among which neurodegenerative, autoimmune, and metabolic diseases. Targeting the NLRP3 inflammasome represents a promising strategy for easing the symptoms of pathologic neuroinflammation.
arxiv   +1 more source

Array-Based Protein Sensing Using an Aggregation-Induced Emission (AIE) Light-Up Probe [PDF]

, 2018
Protein detection and identification are important for the diagnosis of diseases; however, the development of facile sensing probes still remains challenging.
Choi, Huyeon, Kim, Chaekyu, Kim, Sangpil, Lee, Seungho, Ryu, Ja-Hyoung   +4 more
core   +2 more sources

Fabrication and Application of Isotopically Labelled Gold Arrays for Multiplexed Peptide Analysis [PDF]

, 2016
A new array-based technology for the simultaneous capture, chemical labelling and mass spectrometry analysis of peptides is presented. Isotopically labelled self-assembled monolayer (SAM) gold arrays are constructed and used simultaneously to capture and
Batalha, Buckley, Böhm, Chowdhury, Dayon, Gevaert, Gygi, Haddoub, Hudson, Kim, Laurent, Leitner, Ong, Qiu, Qui, Ross, Shi, Shi, Thompson, Valero, Washburn, Zhou, Šardzik, Šardzik   +23 more
core   +1 more source