Results 31 to 40 of about 2,014,238 (321)

Smartphone-Based Quantitative Analysis of Protein Array Signals for Biomarker Detection in Lupus

open access: yesChemosensors, 2022
Fluorescence-based microarray offers great potential in clinical diagnostics due to its high-throughput capability, multiplex capabilities, and requirement for a minimal volume of precious clinical samples.
Guang Yang   +5 more
doaj   +1 more source

CF-PPiD technology based on cell-free protein array and proximity biotinylation enzyme for in vitro direct interactome analysis

open access: yesScientific Reports, 2022
Protein–protein interaction (PPI) analysis is a key process to understand protein functions. Recently, we constructed a human protein array (20 K human protein beads array) consisting of 19,712 recombinant human proteins produced by a wheat cell-free ...
Shusei Sugiyama   +6 more
doaj   +1 more source

Reverse-Phase Protein Array: Technology, Application, Data Processing, and Integration.

open access: yesJournal of Biomolecular Techniques, 2021
Reverse-phase protein array (RPPA) is a high-throughput antibody-based targeted proteomics platform that can quantify hundreds of proteins in thousands of samples derived from tissue or cell lysates, serum, plasma, or other body fluids.
C. Coarfa   +9 more
semanticscholar   +1 more source

In situ structural analysis of Golgi intracisternal protein arrays [PDF]

open access: yesProceedings of the National Academy of Sciences, 2015
Significance To our knowledge, this is the first detailed study of Golgi ultrastructure within unperturbed cells. Three intracisternal structures were identified, with implications for Golgi architecture and trafficking: ( i ) Bundles of filaments show how cargoes may ...
Engel, Benjamin D.   +5 more
openaire   +5 more sources

Pro-MAP: a robust pipeline for the pre-processing of single channel protein microarray data

open access: yesBMC Bioinformatics, 2022
Background The central role of proteins in diseases has made them increasingly attractive as therapeutic targets and indicators of cellular processes. Protein microarrays are emerging as an important means of characterising protein activity.
Metoboroghene Oluwaseyi Mowoe   +6 more
doaj   +1 more source

Analyzing the Impact of Diesel Exhaust Particles on Lung Fibrosis Using Dual PCR Array and Proteomics: YWHAZ Signaling

open access: yesToxics, 2023
Air pollutants are associated with exacerbations of asthma, chronic bronchitis, and airway inflammation. Diesel exhaust particles (DEPs) can induce and worsen lung diseases.
Byeong-Gon Kim   +3 more
doaj   +1 more source

A Network-based Analysis of Polyanion-binding Proteins Utilizing Yeast Protein Arrays [PDF]

open access: yesMolecular & Cellular Proteomics, 2006
The high affinity of certain cellular polyanions for many proteins (polyanion-binding proteins (PABPs)) has been demonstrated previously. It has been hypothesized that such polyanions may be involved in protein structure stabilization, stimulation of folding through chaperone-like activity, and intra- and extracellular protein transport as well as ...
Salamat-Miller, N.   +6 more
openaire   +3 more sources

Profiling of Measles-Specific Humoral Immunity in Individuals Following Two Doses of MMR Vaccine Using Proteome Microarrays

open access: yesViruses, 2015
Introduction: Comprehensive evaluation of measles-specific humoral immunity after vaccination is important for determining new and/or additional correlates of vaccine immunogenicity and efficacy.
Iana H. Haralambieva   +6 more
doaj   +1 more source

A Network-based Analysis of Polyanion-binding Proteins Utilizing Human Protein Arrays [PDF]

open access: yesJournal of Biological Chemistry, 2007
The existence of interactions between many cellular proteins and various polyanionic surfaces within a cell is now well established. The functional role of such interactions, however, remains to be clearly defined. The existence of protein arrays, with a large selection of different kinds of proteins, provides a way to better address a number of ...
Salamat-Miller, N.   +5 more
openaire   +3 more sources

Analysis of patients with colorectal cancer shows a specific increase in serum anti-ING1 autoantibody levels

open access: yesBMC Cancer, 2023
Colorectal cancer (CRC) is the third most prevalent cancer in the world, yet the sensitivity and specificity of biomarkers for CRC diagnosis are insufficient.
Takahiro Arasawa   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy