Assembly and dynamic regulation of the tip filament of the Bordetella type III secretion system injectisome [PDF]
mBioMany gram-negative bacteria utilize a type III secretion system (T3SS) injectisome to translocate effector proteins directly into host cells. In Bordetella bronchiseptica, a respiratory pathogen of diverse mammals, the T3SS injectisome contains a unique ...
Ivana Malcova +3 more
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The Structural Biology of Septins and Their Filaments: An Update
Frontiers in Cell and Developmental Biology, 2021 In order to fully understand any complex biochemical system from a mechanistic point of view, it is necessary to have access to the three-dimensional structures of the molecular components involved. Septins and their oligomers, filaments and higher-order
Italo A. Cavini +8 more
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Disease-related cardiac troponins alter thin filament Ca2+ association and dissociation rates. [PDF]
PLoS ONE, 2012 The contractile response of the heart can be altered by disease-related protein modifications to numerous contractile proteins. By utilizing an IAANS labeled fluorescent troponin C, [Formula: see text], we examined the effects of ten disease-related ...
Bin Liu +4 more
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Multiple sites in αB-crystallin modulate its interactions with desmin filaments assembled in vitro. [PDF]
PLoS ONE, 2011 The β3- and β8-strands and C-terminal residues 155-165 of αB-crystallin were identified by pin arrays as interaction sites for various client proteins including the intermediate filament protein desmin.
Scott A Houck +3 more
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Thick filament‐associated myosin undergoes frequent replacement at the tip of the thick filament
FEBS Open Bio, 2022 Myosin plays a fundamental role in muscle contraction. Approximately 300 myosins form a bipolar thick filament, in which myosin is continuously replaced by protein turnover.
Emi Ichimura +4 more
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Biomolecules, 2021 Bacterial flagella are cell surface protein appendages that are critical for motility and pathogenesis. Flagellar filaments are tubular structures constructed from thousands of copies of the protein flagellin, or FliC, arranged in helical fashion ...
Marko Nedeljković +3 more
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The force of the myosin motor sets cooperativity in thin filament activation of skeletal muscles
Communications Biology, 2022 Sarcomeres of Ca2 + -activated demembranated fibres of rabbit soleus muscles show that the stress exerted by each motor protein on the thin filament determines the cooperativity in thin filament activation.
Marco Caremani +9 more
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Molecular Model of the Microvillar Cytoskeleton and Organization of the Brush Border [PDF]
, 2010 BACKGROUND. Brush border microvilli are ~1-µm long finger-like projections emanating from the apical surfaces of certain, specialized absorptive epithelial cells.
Brown, Jeffrey W., McKnight, C. James
core +9 more sources
Structural and Functional Studies of H. seropedicae RecA Protein - Insights into the Polymerization of RecA Protein as Nucleoprotein Filament. [PDF]
PLoS ONE, 2016 The bacterial RecA protein plays a role in the complex system of DNA damage repair. Here, we report the functional and structural characterization of the Herbaspirillum seropedicae RecA protein (HsRecA). HsRecA protein is more efficient at displacing SSB
Wellington C Leite +9 more
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Distribution of glial fibrillary acidic protein in different parts of the rat brain under cadmium exposure [PDF]
The Ukrainian Biochemical Journal, 2015 The chronic effects of low doses of cadmium on the distribution of soluble and filament forms of glial fibrillary acidic protein (GFAP) and their polypeptide fragments in different parts of the rat brain were investigated.
Yu. P. Kovalchuk +6 more
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