Results 1 to 10 of about 5,231,311 (300)
Scientific Reports, 2022 Vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex that regulates endosomal trafficking in eukaryotic cells. Recent studies have shown that VPS35 promotes tumor cell proliferation and affects the nuclear accumulation of its ...
Xian Hong +9 more
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BMC Cancer, 2021 Background Anterior gradient-2 (AGR2) is a proto-oncogene involved in tumorigenesis and cancer progression. AGR2, predominantly localized in the endoplasmic reticulum (ER), is also a secreted protein detected in the extracellular compartment in multiple ...
Xian Hong +9 more
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Going the distance for protein function prediction: a new distance metric for protein interaction networks [PDF]
, 2013 Due to an error introduced in the production process, the x-axes in the first panels of Figure 1 and Figure 7 are not formatted correctly. The correct Figure 1 can be viewed here: http://dx.doi.org/10.1371/annotation/343bf260-f6ff-48a2-93b2 ...
Cao, Mengfei +6 more
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WASH interacts with Ku to regulate DNA double-stranded break repair
iScience, 2022 Summary: The Wiskott-Aldrich syndrome protein and SCAR homolog (WASH), an actin nucleation-promoting factor, is present in the nucleus where it regulates gene transcription and maintains nuclear organization.
Tao Wang +9 more
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Cell Communication and Signaling, 2020 Background Cancer stem cells (CSCs), the major driver of tumorigenesis, is a sub-population of tumor cells responsible for poor clinical outcomes. However, molecular mechanism to identify targets for controlling CSCs is poorly understood.
Yong-Hee Cho +7 more
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Phytopathology Research, 2023 The 3-ketoacyl-ACP synthase III (FabH), a key enzyme for bacteria growth, catalyses the last step of the initiation of bacterial fatty acid synthesis. Rice bacterial blight is caused by the pathogen Xanthomonas oryzae pv.
Mingfeng Yan +9 more
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npj Biofilms and Microbiomes, 2023 Urban microbiome plays crucial roles in human health and are related to various diseases. The MetaSUB Consortium has conducted the most comprehensive global survey of urban microbiomes to date, profiling microbial taxa/functional genes across 60 cities ...
Yang Chen +8 more
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WDR76 degrades RAS and suppresses cancer stem cell activation in colorectal cancer
Cell Communication and Signaling, 2019 Background Stabilization of RAS is a key event for the hyper-activation of Wnt/β-catenin signaling and activation of cancer stem cell (CSC) in colorectal cancer (CRC).
Eun Ji Ro +5 more
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Biases in the Experimental Annotations of Protein Function and their Effect on Our Understanding of Protein Function Space [PDF]
, 2013 The ongoing functional annotation of proteins relies upon the work of curators to capture experimental findings from scientific literature and apply them to protein sequence and structure data.
Babbitt, Patricia +5 more
core +4 more sources
Microbial Cell Factories, 2020 Porcine growth hormone (pGH) is a class of peptide hormones secreted from the pituitary gland, which can significantly improve growth and feed utilization of pigs. However, it is unstable and volatile in vitro.
Jinbo Deng +12 more
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