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Protein multi-functionality: introduction
Cellular and Molecular Life Sciences, 2019The five articles in this multi-author review in CMLS provide examples of multi-functionality of proteins belonging to several families. Distinct structural features of proteins suggesting multi-functionality are emphasized: intrinsically disordered elements that can "mold" themselves to fit various binding partners, as well as short linear motifs ...
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Protein-Functionalized Hairy Diamond Nanoparticles
Langmuir, 2009Diazonium salt chemistry and atom transfer radical polymerization (ATRP) were combined in view of preparing new bioactive hairy diamond nanoparticles containing, or potentially containing, nitrogen-vacancy (NV) fluorescent centers (fluorescent nanodiamonds, or fNDs). fNDs were modified by ATRP initiators using the electroless reduction of the diazonium
Dahoumane, Si Amar +5 more
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Prediction of Protein Functions
2011The recent explosion in the number and diversity of novel proteins identified by the large-scale "omics" technologies poses new and important questions to the blossoming field of systems biology--what are all these proteins, how did they come about, and most importantly, what do they do? From a comparatively small number of protein structural domains a
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Globularity and Protein Function
Journal of Biomolecular Structure and Dynamics, 2000Abstract The forces that direct protein folding lead naturally to native proteins and protein domains that are typically, to a first approximation, globular-spherical and compact, with a relatively clear distinction between the hydrophobic inside and polar outside.
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Scoring functions for protein–protein interactions
Current Opinion in Structural Biology, 2013The computational evaluation of protein-protein interactions will play an important role in organising the wealth of data being generated by high-throughput initiatives. Here we discuss future applications, report recent developments and identify areas requiring further investigation.
Iain H, Moal +3 more
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Dry Bean Protein Functionality
Critical Reviews in Biotechnology, 2002Dry beans are an important source of proteins, carbohydrates, dietary fiber, and certain minerals and vitamins in the human food supply. Among dry beans, Phaseolus beans are cultivated and consumed in the greatest quantity on a worldwide basis. Typically, most dry beans contain 15 to 25% protein on a dry weight basis (dwb).
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Empirical Protein Partition Functions
The Journal of Physical Chemistry B, 2012In the present paper, we outline how to construct the partition function for a protein using empirical heat capacity data. The procedure is based on the calculation of a set of energy moments from the temperature dependence of the heat capacity. Given a set of energy moments, one can then use the maximum-entropy method to calculate an approximate ...
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Proteins: Dynamics and Function
1988The focus in my paper changes from the genes to gene products, which are proteins. I will describe some of the results of theoretical methods that are used to understand the functioning of these gene products. Since there is no plan for a “human protein consortium,” I will restrict myself to describing what has been going on in this area.
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Functional genomics with protein-protein interactions
2000Knowing the sequence of a gene does not mean knowing its function. Although, information stored at the DNA level can be used to predict biological processes, proteins are the final executors of the various response programs of a cell. Transient information, like posttranslational modifications or interactions among proteins, cannot be deduced from DNA ...
F, Rudert, L, Ge, L L, Ilag
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