Results 1 to 10 of about 543,220 (340)

Reconstructing genome-wide protein-protein interaction networks using multiple strategies with homologous mapping. [PDF]

PLoS ONE, 2015
BACKGROUND:One of the crucial steps toward understanding the biological functions of a cellular system is to investigate protein-protein interaction (PPI) networks.
Yu-Shu Lo, Sing-Han Huang, Yong-Chun Luo, Chun-Yu Lin, Jinn-Moon Yang   +4 more
doaj   +3 more sources

Systematic protein–protein interaction mapping for clinically relevant human GPCRs [PDF]

Molecular Systems Biology, 2017
G‐protein‐coupled receptors (GPCRs) are the largest family of integral membrane receptors with key roles in regulating signaling pathways targeted by therapeutics, but are difficult to study using existing proteomics technologies due to their complex ...
Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi‐Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar   +27 more
doaj   +2 more sources

From nonspecific DNA-protein encounter complexes to the prediction of DNA-protein interactions. [PDF]

PLoS Computational Biology, 2009
DNA-protein interactions are involved in many essential biological activities. Because there is no simple mapping code between DNA base pairs and protein amino acids, the prediction of DNA-protein interactions is a challenging problem. Here, we present a
Mu Gao, Jeffrey Skolnick
doaj   +7 more sources

A simple contact mapping algorithm for identifying potential peptide mimetics in protein–protein interaction partners [PDF]

, 2014
A simple, static contact mapping algorithm has been developed as a first step at identifying potential peptide biomimetics from protein interaction partner structure files.
Alex Krall, Jonathan Brunn, Spandana Kankanala, Michael H. Peters   +3 more
openalex   +5 more sources

Author Correction: Systematic protein-protein interaction mapping for clinically relevant human GPCRs [PDF]

Molecular Systems Biology
Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi-Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar   +27 more
doaj   +2 more sources

Mapping of domain-mediated protein-protein interaction by SPOT peptide assay

STAR Protocols, 2021
Summary: Identification of peptides mediating protein-protein interaction (PPI) is crucial for understanding the function of interlinked proteins in cellular processes and amino acid-associated diseases.
Xiaoyi Mao, Godwin Sokpor, Jochen Staiger, Huu Phuc Nguyen, Tran Tuoc   +4 more
doaj   +1 more source

Mapping of protein-protein interaction sites in the plant-type [2Fe-2S] ferredoxin. [PDF]

PLoS ONE, 2011
Knowing the manner of protein-protein interactions is vital for understanding biological events. The plant-type [2Fe-2S] ferredoxin (Fd), a well-known small iron-sulfur protein with low redox potential, partitions electrons to a variety of Fd-dependent ...
Haruka Kameda, Kei Hirabayashi, Kei Wada, Keiichi Fukuyama   +3 more
doaj   +1 more source

Proteome-wide prediction and analysis of the Cryptosporidium parvum protein–protein interaction network through integrative methods

Computational and Structural Biotechnology Journal, 2022
As one of the most studied Apicomplexan parasite Cryptosporidium, Cryptosporidium parvum (C. parvum) causes worldwide serious diarrhea disease cryptosporidiosis, which can be deadly to immunodeficiency individuals, newly born children, and animals ...
Panyu Ren, Xiaodi Yang, Tianpeng Wang, Yunpeng Hou, Ziding Zhang   +4 more
doaj   +1 more source

Mapping Transcriptome Data to Protein–Protein Interaction Networks of Inflammatory Bowel Diseases Reveals Disease-Specific Subnetworks

Frontiers in Genetics, 2021
Inflammatory bowel disease (IBD) is the common name for chronic disorders associated with the inflammation of the gastrointestinal tract. IBD is triggered by environmental factors in genetically susceptible individuals and has a significant number of ...
Sefika Feyza Maden, Saliha Ece Acuner
doaj   +1 more source

GST‐IVTT pull‐down: a fast and versatile in vitro method for validating and mapping protein–protein interactions

FEBS Open Bio, 2022
Over the past few decades, dozens of in vitro methods have been developed to map, investigate and validate protein–protein interactions. However, most of these approaches are time‐consuming and labour‐intensive or require specialised equipment or ...
Zsuzsánna Réthi‐Nagy, Edit Ábrahám, Zoltán Lipinszki   +2 more
doaj   +1 more source