Results 1 to 10 of about 1,237,822 (372)
Cost-Effective Mapping of Genetic Interactions in Mammalian Cells
Comprehensive maps of genetic interactions in mammalian cells are daunting to construct because of the large number of potential interactions, ~ 2 × 108 for protein coding genes. We previously used co-inheritance of distant genes from published radiation
Arshad H. Khan, Desmond J. Smith
doaj +1 more source
From ORFeomes to Protein Interaction Maps in Viruses [PDF]
Although cloned viral ORFeomes are particularly well suited for genome-wide interaction mapping due to the limited size of viral genomes, only a few such studies have been published. Here, we summarize virus interaction mapping projects involving vaccinia virus, hepatitis C virus (HCV), potato virus A (PVA), pea seed-borne mosaic virus (PSbMV), and ...
Uetz, P.+3 more
openaire +3 more sources
Analytical results for stochastically growing networks: connection to the zero range process
We introduce a stochastic model of growing networks where both, the number of new nodes which joins the network and the number of connections, vary stochastically.
P. Erdös, P. K. Mohanty, Sarika Jalan
core +1 more source
A protein interaction landscape of breast cancer
Description Mapping protein interactions driving cancer Cancer is a genetic disease, and much cancer research is focused on identifying carcinogenic mutations and determining how they relate to disease progression.
Minkyu Kim+27 more
semanticscholar +1 more source
Diplomats or Defendants? Defining the Future of Head-of-State Immunity [PDF]
Fluorescence nanoscopy provides means to discernthe finer details of protein localization and interaction in cells by offeringan order of magnitude higher resolution than conventional optical imagingtechniques.
Amelie Eriksson Karlström+6 more
core +3 more sources
Protein and genetic interaction maps can reveal the overall physical and functional landscape of a biological system. To date, these interaction maps have typically been generated under a single condition, even though biological systems undergo ...
Trey Ideker, Nevan J Krogan
doaj +1 more source
Automated data integration for developmental biological research [PDF]
In an era exploding with genome-scale data, a major challenge for developmental biologists is how to extract significant clues from these publicly available data to benefit our studies of individual genes, and how to use them to improve our understanding
Sternberg, Paul W., Zhong, Weiwei
core +1 more source
Epitope mapping using mRNA display and a unidirectional nested deletion library [PDF]
In vitro selection targeting an anti-polyhistidine monoclonal antibody was performed using mRNA display with a random, unconstrained 27-mer peptide library.
Ja, William W.+2 more
core +1 more source
Synthesis of PRRSV RNAs within host cells depends on the efficient and correct assembly of RTC that takes places on modified intracellular membranes. As an important step toward dissecting this poorly understood event, we investigated the interaction ...
Jiangwei Song+11 more
semanticscholar +1 more source
Drosophila Protein interaction Map (DPiM) [PDF]
Proteins perform essential cellular functions as part of protein complexes, often in conjunction with RNA, DNA, metabolites and other small molecules. The genome encodes thousands of proteins but not all of them are expressed in every cell type; and expressed proteins are not active at all times.
Guruharsha, K.G.+6 more
openaire +4 more sources