Results 21 to 30 of about 1,237,822 (372)

Protein interaction mapping on a functional shotgun sequence of Rickettsia sibirica [PDF]

Nucleic Acids Research, 2004
Protein interaction maps can reveal novel pathways and functional complexes, allowing 'guilt by association' annotation of uncharacterized proteins.
Joel A. Malek
openalex   +2 more sources

Protein interaction mapping interpretation of none alcoholic fatty liver disease model of rats after fat diet feeding. [PDF]

Gastroenterol Hepatol Bed Bench, 2017
Aim: This study investigates the effect of fat diet on gene expression profile in rat liver via protein-protein interaction mapping analysis. Background: Nonalcoholic fatty liver disease (NAFLD) is a prevalent condition of liver in the world.
Abdollahi H, Zamanian Azodi M, Hatami B.
europepmc   +2 more sources

Mass spectrometry‐based protein–protein interaction networks for the study of human diseases

Molecular Systems Biology, 2021
A better understanding of the molecular mechanisms underlying disease is key for expediting the development of novel therapeutic interventions. Disease mechanisms are often mediated by interactions between proteins. Insights into the physical rewiring of
Alicia L Richards, Manon Eckhardt, Nevan J Krogan   +2 more
doaj   +2 more sources

Protein Interaction Mapping Identifies RBBP6 as a Negative Regulator of Ebola Virus Replication. [PDF]

Cell, 2018
Batra J, Hultquist JF, Liu D, Shtanko O, Von Dollen J, Satkamp L, Jang GM, Luthra P, Schwarz TM, Small GI, Arnett E, Anantpadma M, Reyes A, Leung DW, Kaake R, Haas P, Schmidt CB, Schlesinger LS, LaCount DJ, Davey RA, Amarasinghe GK, Basler CF, Krogan NJ.   +22 more
europepmc   +2 more sources

Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis. [PDF]

Cell, 2018
Shah PS, Link N, Jang GM, Sharp PP, Zhu T, Swaney DL, Johnson JR, Von Dollen J, Ramage HR, Satkamp L, Newton B, Hüttenhain R, Petit MJ, Baum T, Everitt A, Laufman O, Tassetto M, Shales M, Stevenson E, Iglesias GN, Shokat L, Tripathi S, Balasubramaniam V, Webb LG, Aguirre S, Willsey AJ, Garcia-Sastre A, Pollard KS, Cherry S, Gamarnik AV, Marazzi I, Taunton J, Fernandez-Sesma A, Bellen HJ, Andino R, Krogan NJ.   +35 more
europepmc   +2 more sources

Quantitative interaction mapping reveals an extended UBX domain in ASPL that disrupts functional p97 hexamers

Nature Communications, 2016
The AAA+ ATPase p97 is an essential hexameric protein with multiple protein interaction partners and cellular functions. Here, the authors use interaction mapping to examine partner proteins of this large complex, and assess the effects of these proteins
Anup Arumughan, Yvette Roske, Carolin Barth, Laura Lleras Forero, Kenny Bravo-Rodriguez, Alexandra Redel, Simona Kostova, Erik McShane, Robert Opitz, Katja Faelber, Kirstin Rau, Thorsten Mielke, Oliver Daumke, Matthias Selbach, Elsa Sanchez-Garcia, Oliver Rocks, Daniela Panáková, Udo Heinemann, Erich E. Wanker   +18 more
doaj   +2 more sources

Mitochondrial Protein Interaction Mapping Identifies Regulators of Respiratory Chain Function. [PDF]

Mol Cell, 2016
Floyd BJ, Wilkerson EM, Veling MT, Minogue CE, Xia C, Beebe ET, Wrobel RL, Cho H, Kremer LS, Alston CL, Gromek KA, Dolan BK, Ulbrich A, Stefely JA, Bohl SL, Werner KM, Jochem A, Westphall MS, Rensvold JW, Taylor RW, Prokisch H, Kim JP, Coon JJ, Pagliarini DJ.   +23 more
europepmc   +2 more sources

Intracellular protein interaction mapping with FRET hybrids [PDF]

Proceedings of the National Academy of Sciences, 2006
A quantitative methodology was developed to identify protein interactions in a broad range of cell types by using FRET between fluorescent proteins. Genetic fusions of a target receptor to a FRET acceptor and a large library of candidate peptide ligands to a FRET donor enabled high-throughput optical screening for optimal interaction ...
Xia You, Annalee W. Nguyen, Abeer M. Jabaiah, Mark A. Sheff, K. Thorn, P. Daugherty   +5 more
semanticscholar   +4 more sources

A Partitioned Approach to Protein Interaction Mapping [PDF]

International Symposium Graph Drawing and Network Visualization, 2002
This is a brief description of a new program for drawing protein interactions in three-dimensional space. Our program divides nodes into three groups: biconnected subgraph in the center, terminal nodes at the outermost region, and the rest in between them.
Yanga Byun, Euna Jeong, Kyungsook Han
semanticscholar   +3 more sources

Author Correction: Systematic protein-protein interaction mapping for clinically relevant human GPCRs [PDF]

Molecular Systems Biology
Kate Sokolina, Saranya Kittanakom, Jamie Snider, Max Kotlyar, Pascal Maurice, Jorge Gandía, Abla Benleulmi-Chaachoua, Kenjiro Tadagaki, Atsuro Oishi, Victoria Wong, Ramy H Malty, Viktor Deineko, Hiroyuki Aoki, Shahreen Amin, Zhong Yao, Xavier Morató, David Otasek, Hiroyuki Kobayashi, Javier Menendez, Daniel Auerbach, Stephane Angers, Natasa Pržulj, Michel Bouvier, Mohan Babu, Francisco Ciruela, Ralf Jockers, Igor Jurisica, Igor Stagljar   +27 more
doaj   +2 more sources