Results 241 to 250 of about 562,686 (340)

NUCLEIC ACID PRECURSORS AND PROTEIN SYNTHESIS [PDF]

Proceedings of the National Academy of Sciences, 1954
openaire   +3 more sources

Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee, Peter Lialios, Micaila Curtis, James Williams IV, Yoontae Kim, Paul Salipante, Steven Hudson, Mandy B. Esch, Moshe Levi, Joanna Kitlinska, Stella Alimperti   +10 more
wiley   +1 more source

Spike-in enhanced phosphoproteomics uncovers synergistic signaling responses to MEK inhibition in colon cancer cells. [PDF]

Nat Commun
van Bentum M, Klinger B, Sieber A, Naghiloo S, Zauber H, Lehmann N, Haji M, Niquet S, Mertins P, Blüthgen N, Selbach M.   +10 more
europepmc   +1 more source

Intracellular and intramitochondrial sorting of precursor proteins [PDF]

, 1987
Neupert, Walter, Ozawa, Takayuki, Papa, S., Schwaiger, Martin   +3 more
core   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

The neuropeptidomes of the sea cucumbers Stichopus cf. horrens and Holothuria scabra. [PDF]

Sci Rep
Resoles JAA, Yu ET.
europepmc   +1 more source

Resolution of distinct steps in mitochondrial protein import [PDF]

, 1988
Bradshaw, Ralph A., Douglas, M. G., Hartl, Franz-Ulrich, McAlister-Henn, L., Neupert, Walter, Pfanner, Nikolaus   +5 more
core  

Translocation of proteins into rat liver mitochondria. Existence of two different precursor polypeptides of liver fumarase and import of the precursor into mitochondria.

, 1985
H Ono, N Yoshimura, Maria Notomi Sato, Syozo Tuboi   +3 more
openalex   +1 more source

Reinforced Polymer–Nanoparticle Hydrogels for Subcutaneous and Sustained Delivery of Trastuzumab

Advanced Healthcare Materials, EarlyView.
Biologic therapy development is rapidly accelerating, requiring extended delivery formulation strategies. Supramolecular hydrogels and electrostatic complexation create subcutaneous depots that release clinically relevant trastuzumab doses in a controlled manner through simple component mixing without chemical modifications.
Giovanni Bovone, Stéphane Bernhard, Guillaume Jacquot, Vincent Mittelheisser, Céline Mirjolet, Elia A. Guzzi, Lorenza Garau Paganella, Luca Liebi, Julien Draussin, Pedro Lopez Navarro, Elsa Barbé, Olivier Lefebvre, Jacky G. Goetz, Loic J. Charbonnière, Xavier Pivot, Sébastien Harlepp, Mark W. Tibbitt, Alexandre Detappe   +17 more
wiley   +1 more source

Investigation of Fibrillar Aggregates Formed by Pathogenic Pre-pro-vasopressin Mutants that Cause ADNDI.

J Clin Endocrinol Metab
Vaizoglu RD, Erdem B, Gul M, Acar C, Ozdemirel HO, Saglar Ozer E, Mergen H.   +6 more
europepmc   +1 more source