Results 21 to 30 of about 4,543,051 (305)
Prediction of type III secretion signals in genomes of gram-negative bacteria [PDF]
, 2009 Background: Pathogenic bacteria infecting both animals as well as plants use various mechanisms to transport virulence factors across their cell membranes and channel these proteins into the infected host cell.
Löwer, Martin +5 more
core +2 more sources
Inhibition of cellular protein secretion by norwalk virus nonstructural protein p22 requires a mimic of an endoplasmic reticulum export signal. [PDF]
, 2013 Protein trafficking between the endoplasmic reticulum (ER) and Golgi apparatus is central to cellular homeostasis. ER export signals are utilized by a subset of proteins to rapidly exit the ER by direct uptake into COPII vesicles for transport to the ...
Estes, M. K. +4 more
core +3 more sources
Nature Communications, 2019 Reliable methods of measuring intracellular H2O2 fluctuations are necessary to advance redox biology. Here the authors design a H2O2 sensor based on the fission yeast peroxiredoxin Tpx1 to sense nanomolar fluctuations of intracellular H2O2 in response to
Mercè Carmona +8 more
doaj +1 more source
mBio, 2017 Sophisticated nanomachines are used by bacteria for protein secretion. In Gram-negative bacteria, the type 2 secretion system (T2SS) is composed of a pseudopilus assembly platform in the inner membrane and a secretin complex in the outer membrane.
Iain D. Hay +2 more
doaj +1 more source
Protein secretion in streptomycetes [PDF]
FEMS Microbiology Letters, 2006 Some aspects of the current knowledge on protein secretion in streptomycetes are presented including recent data on the identification of genes in the general secretory pathway, on the importance of the signal peptide structure and on the number of ribosome-binding sites inside signal peptides which can influence the production level of a gene product.
R, Morosoli, F, Shareck, D, Kluepfel
openaire +2 more sources
CagI is an essential component of the Helicobacter pylori Cag type IV secretion system and forms a complex with CagL. [PDF]
, 2012 Helicobacter pylori, the causative agent of type B gastritis, peptic ulcers, gastric adenocarcinoma and MALT lymphoma, uses the Cag type IV secretion system to induce a strong proinflammatory response in the gastric mucosa and to inject its effector ...
Haas, Rainer +17 more
core +2 more sources
Distribution and diversity of bacterial secretion systems across metagenomic datasets [PDF]
, 2012 Bacteria can manipulate their surrounding environment through the secretion of proteins into other living organisms and into the extracellular milieu. In Gram stain negative bacteria this process is mediated by different types of secretion systems from ...
Egan, Frank +3 more
core +1 more source
Microbial Cell Factories, 2019 Background The yeast Pichia pastoris is a widely used host for the secretion of heterologous proteins. Despite being an efficient producer, we observed previously that certain recombinant proteins were mistargeted to the vacuole on their route to ...
Lukas Marsalek +4 more
doaj +1 more source
mBio, 2020 Pathogenic mycobacteria encounter multiple environments during macrophage infection. Temporally, the bacteria are engulfed into the phagosome, lyse the phagosomal membrane, and interact with the cytosol before spreading to another cell. Virulence factors
Kevin G. Sanchez +6 more
doaj +1 more source
Microreview: type IV secretion systems: versatility and diversity in function [PDF]
, 2010 Type IV secretion systems (T4SSs) are large protein complexes which traverse the cell envelope of many bacteria. They contain a channel through which proteins or protein–DNA complexes can be translocated.
Angel Rivera-Calzada +5 more
core +1 more source