Results 1 to 10 of about 1,851,770 (264)

Sequence and Structure-Based Analysis of Specificity Determinants in Eukaryotic Protein Kinases

Cell Reports, 2021
Summary: Protein kinases lie at the heart of cell-signaling processes and are often mutated in disease. Kinase target recognition at the active site is in part determined by a few amino acids around the phosphoacceptor residue. However, relatively little
David Bradley, Cristina Viéitez, Vinothini Rajeeve, Joel Selkrig, Pedro R. Cutillas, Pedro Beltrao   +5 more
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Analysis of protein sequences [PDF]

Genome Biology, 2000
Several programs to predict sequence and structural features of a protein can be run simultaneously on the PredictProtein server.
openaire   +1 more source

Protein Sequence Retrieval and Phylogenetic Analysis of Various α-amylase Producing Bacillus species [PDF]

International Journal Bioautomation, 2020
Due to advancements made in biotechnology, genetic manipulation and medium optimization has been possible and that has led to high yield in enzyme especially α-amylase with improvised properties that find its application suitably in detergent, laundry ...
Sonali Priyadarshini, Sukanta Kumar Pradhan, Pratima Ray   +2 more
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Predicting the Specificity- Determining Positions of Receptor Tyrosine Kinase Axl

Frontiers in Molecular Biosciences, 2021
Owing to its clinical significance, modulation of functionally relevant amino acids in protein-protein complexes has attracted a great deal of attention.
Tülay Karakulak, Tülay Karakulak, Tülay Karakulak, Tülay Karakulak, Tülay Karakulak, Ahmet Sureyya Rifaioglu, João P. G. L. M. Rodrigues, Ezgi Karaca, Ezgi Karaca   +8 more
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Comparison study on k-word statistical measures for protein: From sequence to 'sequence space'

BMC Bioinformatics, 2008
Background Many proposed statistical measures can efficiently compare protein sequence to further infer protein structure, function and evolutionary information. They share the same idea of using k-word frequencies of protein sequences.
Wang Tianming, Dai Qi
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The Computer‐Assisted Sequence Annotation (CASA) workflow for enzyme discovery

Applications in Plant Sciences
Premise With the advent of inexpensive nucleic acid sequencing and automated annotation at the level of basic functionality, the central problem of enzyme discovery is no longer finding active sequences, it is determining which ones are suitable for ...
Gemma R. Takahashi, Franchesca M. Cumpio, Carter T. Butts, Rachel W. Martin   +3 more
doaj   +1 more source

Combining handcrafted and learned features using deep learning to improve protein-protein interaction prediction performance

Journal of Information and Telecommunication
Understanding protein-protein interactions (PPIs) is essential because knowledge regarding PPIs helps in determining the biochemical functions of organisms. Advances made in machine learning techniques, for example, DeepFE-PPI, GcForest-PPI, and DeepPPI,
Tran Hoai Nhan, Nguyen Phuc Xuan Quynh, Le Anh Phuong   +2 more
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A Protein Sequence Analysis Hardware Accelerator Based on Divergences

International Journal of Reconfigurable Computing, 2012
The Viterbi algorithm is one of the most used dynamic programming algorithms for protein comparison and identification, based on hidden markov Models (HMMs).
Juan Fernando Eusse, Nahri Moreano, Alba Cristina Magalhaes Alves de Melo, Ricardo Pezzuol Jacobi   +3 more
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Genetic Diversity and Prevalence of Porcine Circovirus Type 2 in China During 2000-2019

Frontiers in Veterinary Science, 2021
As the major pathogen for porcine circovirus-associated disease (PCVAD), porcine circovirus type 2 (PCV2) is no longer treated as an emerging virus anymore.
Ning Li, Jing Liu, Jiali Qi, Feng Hao, Lei Xu, Kangkang Guo   +5 more
doaj   +1 more source

DispHScan: A Multi-Sequence Web Tool for Predicting Protein Disorder as a Function of pH

Biomolecules, 2021
Proteins are exposed to fluctuating environmental conditions in their cellular context and during their biotechnological production. Disordered regions are susceptible to these fluctuations and may experience solvent-dependent conformational switches ...
Carlos Pintado-Grima, Valentín Iglesias, Jaime Santos, Vladimir N. Uversky, Salvador Ventura   +4 more
doaj   +1 more source