Results 11 to 20 of about 1,851,770 (264)

MESSA: MEta-Server for protein Sequence Analysis [PDF]

open access: yesBMC Biology, 2012
Background Computational sequence analysis, that is, prediction of local sequence properties, homologs, spatial structure and function from the sequence of a protein, offers an efficient way to obtain needed information about proteins under study.
Cong Qian, Grishin Nick V
doaj   +2 more sources

Herding cats: Label-based approaches in protein translocation through nanopore sensors for single-molecule protein sequence analysis [PDF]

open access: yesiScience, 2021
Summary: Proteins carry out life's essential functions. Comprehensive proteome analysis technologies are thus required for a full understanding of the operating principles of biological systems. While current proteomics techniques suffer from limitations
Keisuke Motone   +2 more
doaj   +2 more sources

Protein sequence analysis in the context of drug repurposing [PDF]

open access: yesBMC Medical Informatics and Decision Making
Motivation Drug repurposing speeds up the development of new treatments, being less costly, risky, and time consuming than de novo drug discovery. There are numerous biological elements that contribute to the development of diseases and, as a result, to ...
Natalia García Sánchez   +3 more
doaj   +2 more sources

Interactive Analysis of Functional Residues in Protein Families

open access: yesmSystems, 2022
A protein’s function depends on functional residues that determine its binding specificity or its catalytic activity, but these residues are typically not considered when annotating a protein’s function.
Morgan N. Price, Adam P. Arkin
doaj   +1 more source

Evolutionary Study of Protein Short Tandem Repeats in Protein Families

open access: yesBiomolecules, 2023
Tandem repeats in proteins are patterns of residues repeated directly adjacent to each other. The evolution of these repeats can be assessed by using groups of homologous sequences, which can help pointing to events of unit duplication or deletion.
Pablo Mier, Miguel A. Andrade-Navarro
doaj   +1 more source

Analysis of the Sequence Characteristics of Antifreeze Protein

open access: yesLife, 2021
Antifreeze protein (AFP) is a proteinaceous compound with improved antifreeze ability and binding ability to ice to prevent its growth. As a surface-active material, a small number of AFPs have a tremendous influence on the growth of ice.
Yu-Hang Zhang   +7 more
doaj   +1 more source

GWideCodeML: A Python Package for Testing Evolutionary Hypotheses at the Genome-Wide Level

open access: yesG3: Genes, Genomes, Genetics, 2020
One of the most widely used programs for detecting positive selection, at the molecular level, is the program codeml, which is implemented in the Phylogenetic Analysis by Maximum Likelihood (PAML) package.
Laura G. Macías   +2 more
doaj   +1 more source

A sequence embedding method for enzyme optimal condition analysis

open access: yesBMC Bioinformatics, 2020
Background An enzyme activity is influenced by the external environment. It is important to have an enzyme remain high activity in a specific condition.
Xiangjun Li   +5 more
doaj   +1 more source

Protocol for the prediction, interpretation, and mutation evaluation of post-translational modification using MIND-S

open access: yesSTAR Protocols, 2023
Summary: Post-translational modifications (PTMs) serve as key regulatory mechanisms in various cellular processes; altered PTMs can potentially lead to human diseases.
Yu Yan   +6 more
doaj   +1 more source

Expression of goat RNA binding protein (NANOS2), development and evaluation of anti-NANOS2 IgY antibodies

open access: yesCzech Journal of Animal Science, 2015
Available rabbit anti-NANOS2 antibodies failed to recognize the NANOS2 protein of goat origin though they showed better reactivity towards the same protein of human and mice origin.
X. Yao   +8 more
doaj   +1 more source

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