Results 31 to 40 of about 1,631,952 (291)

Linkers of secondary structures in proteins [PDF]

open access: yesProtein Science, 1997
AbstractLinkers that connect repeating secondary structures fall into conformational classes based on distance and main‐chain torsion clustering. A data set of 300 unique protein chains with low pairwise sequence identity was clustered into only a few groups representing the preferred motifs.
V, Geetha, P J, Munson
openaire   +2 more sources

NMR solution structure of a chymotrypsin inhibitor from the Taiwan cobra Naja naja atra [PDF]

open access: yes, 2013
The Taiwan cobra (Naja naja atra) chymotrypsin inhibitor (NACI) consists of 57 amino acids and is related to other Kunitz-type inhibitors such as bovine pancreatic trypsin inhibitor (BPTI) and Bungarus fasciatus fraction IX (BF9), another chymotrypsin ...
Chang, Long-Sen   +3 more
core   +2 more sources

Combining protein evolution and secondary structure [PDF]

open access: yesMolecular Biology and Evolution, 1996
An evolutionary model that combines protein secondary structure and amino acid replacement is introduced. It allows likelihood analysis of aligned protein sequences and does not require the underlying secondary (or tertiary) structures of these sequences to be known.
J L, Thorne, N, Goldman, D T, Jones
openaire   +2 more sources

Extracting Physicochemical Features to Predict Protein Secondary Structure

open access: yesThe Scientific World Journal, 2013
We propose a protein secondary structure prediction method based on position-specific scoring matrix (PSSM) profiles and four physicochemical features including conformation parameters, net charges, hydrophobic, and side chain mass.
Yin-Fu Huang, Shu-Ying Chen
doaj   +1 more source

A Hierarchical Approach to Protein Molecular Evolution [PDF]

open access: yes, 1999
Biological diversity has evolved despite the essentially infinite complexity of protein sequence space. We present a hierarchical approach to the efficient searching of this space and quantify the evolutionary potential of our approach with Monte Carlo ...
Crameri   +30 more
core   +2 more sources

Extended secondary structures in proteins

open access: yesBiochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2014
Super secondary structures of proteins have been systematically searched and classified, but not enough attention has been devoted to such large edifices beyond the basic identification of secondary structures. The objective of the present study is to show that the association of secondary structures that share some of their backbone residues is a ...
Degrève, Léo   +2 more
openaire   +2 more sources

Factors affecting sorghum protein digestibility [PDF]

open access: yes, 2003
In the semi-arid tropics worldwide, sorghum (Sorghum bicolor (L.) Moench) is cultivated by farmers on a subsistence level and consumed as food by humans.
Belton, Peter   +3 more
core   +1 more source

MAS NMR detection of hydrogen bonds for protein secondary structure characterization [PDF]

open access: yes, 2020
Hydrogen bonds are essential for protein structure and function, making experimental access to long-range interactions between amide protons and heteroatoms invaluable. Here we show that measuring distance restraints involving backbone hydrogen atoms and
Friedrich, Daniel   +3 more
core   +1 more source

An evolutionary method for learning HMM structure: prediction of protein secondary structure

open access: yesBMC Bioinformatics, 2007
Background The prediction of the secondary structure of proteins is one of the most studied problems in bioinformatics. Despite their success in many problems of biological sequence analysis, Hidden Markov Models (HMMs) have not been used much for this ...
Won Kyoung-Jae   +3 more
doaj   +1 more source

Synthesis and structural characterization of a mimetic membrane-anchored prion protein [PDF]

open access: yes, 2006
During pathogenesis of transmissible spongiform encephalopathies (TSEs) an abnormal form (PrPSc) of the host encoded prion protein (PrPC) accumulates in insoluble fibrils and plaques. The two forms of PrP appear to have identical covalent structures, but
Andrew C. Gill   +44 more
core   +1 more source

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