Results 111 to 120 of about 734,343 (302)

Proteinase Inhibitors of Finger Millet (Eleusine coracana gaertn.)

, 1978
Proteinase inhibitory activities of a number of finger millet and five representative varieties of other millets were determined. Inhibitory activities in the buffer extracts of the millets varied widely.
Virupaksha, T.K., Manjunath, N.H., Veerabhadrappa, P.S.   +2 more
core   +1 more source

Inhibition of post-mortem fish muscle softening and degradation using legume seed proteinase inhibitors. [PDF]

J Food Sci Technol, 2020
Singh J, Singh B.
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Caprine plasma proteinase inhibitors. I. Partial characterization

, 1993
1. 1. Using two-dimensional electrophoresis (IEF, pH 3.5-6.0 and PAGE, 11.5% T, pH 7.9) the caprine plasma proteinase inhibitors were classified into six distinct classes, designated PIa, PIb, PIc, PId, PIe and PIf.
Vankan, D. M., Bell, K.
core   +1 more source

PROTEINASES AND PROTEINASE INHIBITORS IN FERTILIZATION [PDF]

, 1976
Schleuning, W. D., Schießler, Hans, Fink, Edwin, Tschesche, Harald, Fritz, Hans   +4 more
openaire   +2 more sources

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

Regulation and regulatory role of proteinase inhibitors

, 1995
Excess or ill-timed proteolytic events have, of necessity, to be restrained. Therefore, there are partner proteinase inhibitors to most of the known mammalian enzymes that cleave peptide bonds, a situation that implicates the inhibitors in a myriad of ...
Roberts, R. Michael, Mathialagan, Nagappan, Duffy, Jodie Y., Smith, George W.   +3 more
core  

Heterologous Expression of PKPI and Pin1 Proteinase Inhibitors Enhances Plant Fitness and Broad-Spectrum Resistance to Biotic Threats. [PDF]

Front Plant Sci, 2020
Turrà D, Vitale S, Marra R, Woo SL, Lorito M.   +4 more
europepmc   +1 more source

Novel role for proteinase-activated receptor 2 (PAR2) in membrane trafficking of proteinase-activated receptor 4 (PAR4) [PDF]

, 2012
Proteinase-activated receptors 4 (PAR4) is a class A G protein-coupled receptor (GPCR) recognized through the ability of serine proteases such as thrombin and trypsin to mediate receptor activation.
Robben, Joris, Cooke, Alexandra E., Nilsson, Mary, Mundell, Stuart, Plevin, Robin, Cunningham, Margaret R., Gould, Gwyn W., McIntosh, Kathryn A., Milligan, Graeme, Pediani, John D.   +9 more
core   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source