Results 11 to 20 of about 172,761 (292)

The Homology Modeling and Docking Investigation of Human Cathepsin B [PDF]

open access: yesInternational Journal of Medical Toxicology and Forensic Medicine, 2020
Background: Cathepsin B comprises a group of lysosomal cysteine proteases belonging to the Papain family; it has an intracellular function in the process of protein catabolism, antigen processing in the immune response, and Alzheimer’s disease.
Afshin Khara   +2 more
doaj   +1 more source

Identification of three stage-specific proteinases of Plasmodium falciparum. [PDF]

open access: yes, 1987
We have identified and characterized three stage-specific proteinases of Plasmodium falciparum that are active at neutral pH. We analyzed ring-, trophozoite-, schizont-, and merozoite-stage parasites by gelatin substrate PAGE and characterized the ...
Kim, K   +3 more
core   +2 more sources

Pest protection conferred by a Beta vulgaris serine proteinase inhibitor gene. [PDF]

open access: yesPLoS ONE, 2013
Proteinase inhibitors provide a means of engineering plant resistance to insect pests. A Beta vulgaris serine proteinase inhibitor gene (BvSTI) was fused to the constitutive CaMV35S promoter for over-expression in Nicotiana benthamiana plants to study ...
Ann C Smigocki   +3 more
doaj   +1 more source

The effect of dry extract of cabbage garden on the local non-specific proteinase-inhibitory potential of the mucous membrane of the stomach on the model of acute gastric ulcer

open access: yesФармацевтичний журнал, 2019
Peptic ulcer of the stomach and duodenum is a complex gastroenterological disease multifactorial in pathogenesis. One of the key components of non-specific inflammation in peptic ulcer disease is the activation of proteinases in the gastric mucosa and ...
N. N. Kononenko   +2 more
doaj   +1 more source

Results of protease inhibitor instructions in patients in acute burning disease

open access: yesСучасні медичні технології, 2022
The purpose of the study was to determine the clinical efficiency of proteinase inhibitor usage in patients with burns. Materials and Methods. The results of studies performed in 32 patients with superficial and deep burns were analyzed: 12 patients of ...
O.M. Lynnyk, H.P. Kozynets, O.I. Osadcha
doaj   +1 more source

Cysteine peptidases and their inhibitors in breast and genital cancer.

open access: yesFolia Histochemica et Cytobiologica, 2010
Cysteine proteinases and their inhibitors probably play the main role in carcinogenesis and metastasis. The metastasis process need external proteolytic activities that pass several barriers which are membranous structures of the connective tissue which ...
Magdalena Milan   +7 more
doaj   +1 more source

Adhesive and degradative properties of human placental cytotrophoblast cells in vitro. [PDF]

open access: yes, 1989
Human fetal development depends on the embryo rapidly gaining access to the maternal circulation. The trophoblast cells that form the fetal portion of the human placenta have solved this problem by transiently exhibiting certain tumor-like properties ...
Cui, TY   +7 more
core   +3 more sources

EFFECT OF SILVER NANOPARTICLES IN EXPERIMENTAL PERITONITIS

open access: yesБюллетень сибирской медицины, 2015
In our research we have investigated the effect of intraperitoneal introduction of silver nanoparticles solution (linear particle size of 10–20 nm) into intact animals and in the simulation of experimental peritonitis.
D. V. Chegodar   +2 more
doaj   +1 more source

TRANSGENIC PLANTS RESISTANT TO INSECTS [PDF]

open access: yesPoljoprivreda, 2009
Proteinase inhibitors are secondary metabolites present in all plants and it seems that their major role is protection of plants against attacks of animals, insects and microorganisms.
S. Kereša   +4 more
doaj  

Potential therapeutic target identification in the novel 2019 coronavirus: insight from homology modeling and blind docking study

open access: yesEgyptian Journal of Medical Human Genetics, 2020
Background The 2019-nCoV which is regarded as a novel coronavirus is a positive-sense single-stranded RNA virus. It is infectious to humans and is the cause of the ongoing coronavirus outbreak which has elicited an emergency in public health and a call ...
Olanrewaju Ayodeji Durojaye   +7 more
doaj   +1 more source

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