Results 111 to 120 of about 132,694 (329)
Bioinspired Tissue Transparency: Achieving Sclera‐to‐Cornea Transplantation
A bioinspired decellularization‐compression‐locking tactic (DCLT) is developed to transform human sclerae into transparent corneal substitutes. These clear, robust, and pro‐regenerative substitutes are capable of repairing complex corneal injuries, including chemical burns, keratoconus, and penetrating wounds, demonstrating their clinical potential to ...
Xiuli Sun +8 more
wiley +1 more source
Endosomal signalling via exosome surface TGFβ-1
Extracellular vesicles such as exosomes convey biological messages between cells, either by surface-to-surface interaction or by shuttling of bioactive molecules to a recipient cell’s cytoplasm.
Ganesh Vilas Shelke +9 more
doaj +1 more source
Enhanced synthesis and accumulation of proteoglycans in cholesterol-enriched arterial smooth muscle cells [PDF]
Parakat Vijayagopal
openalex +1 more source
Virucidal polymers serve as effective antivirals by not only inhibiting viruses but also destroying them. Inspired by the chemical properties of mucin‐mimetics, dendronized polyglycerol‐sulfated, mucin‐inspired amphiphilic copolymers (MIACPs) have been developed.
Raju Bej +10 more
wiley +1 more source
P1‐445: Glycosaminoglycan sulfate moieties and chain length important for heparan sulfate proteoglycan interactions with amyloid‐beta [PDF]
Nienke Timmer +2 more
openalex +1 more source
Fibronectin on extracellular vesicles from microvascular endothelial cells is involved in the vesicle uptake into oligodendrocyte precursor cells. [PDF]
学位記番号 ...
Osawa, Sho +2 more
core
This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen +10 more
wiley +1 more source
A Systematic Review of Extracellular Matrix-Related Alterations in Parkinson’s Disease
The role of the extracellular matrix (ECM) in Parkinson’s disease (PD) is not well understood, even though it is critical for neuronal structure and signaling.
Mary Ann Chapman, Barbara A. Sorg
doaj +1 more source
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu +10 more
wiley +1 more source
Proteoglycans of the extracellular matrix and growth control [PDF]
Hans Kresse, Elke Schönherr
openalex +1 more source

