Results 141 to 150 of about 110,290 (187)
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Proteoglycans and proteoglycan mimetics for tissue engineering
American Journal of Physiology-Cell Physiology, 2022Proteoglycans play a crucial role in proper tissue morphology and function throughout the body that is defined by a combination of their core protein and the attached glycosaminoglycan chains. Although they serve a myriad of roles, the functions of extracellular proteoglycans can be generally sorted into four categories: modulation of tissue ...
Michael Nguyen, Alyssa Panitch
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Experientia, 1993
In this review the structure and functions of two non-related proteoglycan families are discussed. One family represents a group of extracellular matrix macromolecules characterized by core proteins with leucine-rich repeat motifs. Within this family special attention is given to those members which carry chondroitin or dermatan sulfate ...
H, Kresse, H, Hausser, E, Schönherr
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In this review the structure and functions of two non-related proteoglycan families are discussed. One family represents a group of extracellular matrix macromolecules characterized by core proteins with leucine-rich repeat motifs. Within this family special attention is given to those members which carry chondroitin or dermatan sulfate ...
H, Kresse, H, Hausser, E, Schönherr
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Developmental Neuroscience, 1989
The structure, biosynthesis, localization, and possible functional roles of nervous tissue glycosaminoglycans and proteoglycans were last reviewed several years ago. Since that time, there has been an exponential increase in publications on the neurobiology of proteoglycans.
R U, Margolis, R K, Margolis
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The structure, biosynthesis, localization, and possible functional roles of nervous tissue glycosaminoglycans and proteoglycans were last reviewed several years ago. Since that time, there has been an exponential increase in publications on the neurobiology of proteoglycans.
R U, Margolis, R K, Margolis
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Evidence of proteoglycan/proteoglycan interactions within aggregates
Journal of Orthopaedic Research, 1991AbstractNonaggregated proteoglycan monomers, digested fragments of the monomers, as well as link proteins have been shown to self‐associate. These associations have not been shown to occur on the aggregate. However, previous reports, using the Kleinschmidt technique of monolayer electron microscopy, have noted proteoglycan subunits on the aggregate ...
A, Kahn +3 more
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1994
Abstract Proteoglycans, by definition, are conjugates of protein and glycosaminoglycan which are found largely in connective tissue. Their major role is to provide swelling pressure in these tissues by virtue of a Donnan osmotic effect due to the high fixed negative charge found on these molecules.
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Abstract Proteoglycans, by definition, are conjugates of protein and glycosaminoglycan which are found largely in connective tissue. Their major role is to provide swelling pressure in these tissues by virtue of a Donnan osmotic effect due to the high fixed negative charge found on these molecules.
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Proteoglycans in amyloidogenesis
Neurobiology of Aging, 1989The potentially important role of proteoglycans and glycosaminoglycans in the modern concept of general amyloidogenesis has been discussed.
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Current Pharmaceutical Design, 2017
Most proteoglycans are heterogeneous molecules composed of a protein core with glycosaminoglycans (GAGs) attached. GAGs are highly negatively charged molecules that readily bind to enzymes, growth factors, cytokines etc. and as such have many functions.
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Most proteoglycans are heterogeneous molecules composed of a protein core with glycosaminoglycans (GAGs) attached. GAGs are highly negatively charged molecules that readily bind to enzymes, growth factors, cytokines etc. and as such have many functions.
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Transmembrane Signaling Proteoglycans
Annual Review of Cell and Developmental Biology, 2010Virtually all metazoan cells contain at least one and usually several types of transmembrane proteoglycans. These are varied in protein structure and type of polysaccharide, but the total number of vertebrate genes encoding transmembrane proteoglycan core proteins is less than 10.
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Glycosaminoglycan and proteoglycan in skin aging.
Journal of dermatological science (Amsterdam), 2016Dong Hun Lee, Jang-Hee Oh, J. Chung
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Negative regulation of transforming growth factor-β by the proteoglycan decorin
Nature, 1990Yu Yamaguchi, D. Mann, E. Ruoslahti
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