Results 151 to 160 of about 109,553 (241)

Nanomaterials for promoting axon regeneration after spinal cord injury: Mechanisms and prospects

Interdisciplinary Medicine, EarlyView.
The effects of clinical therapies for spinal cord injury (SCI) are greatly limited due to poor axon regeneration. This review systematically discusses the ability of nanomaterials (NMs) to treat SCI and the mechanism underlying their therapeutic effects. The properties of NMs that are conducive to axon regeneration after SCI are outlined.
Jia Liu, Zhendong Huang, Xiner Tan, Wei Du, Ziyang Wang, Xinru Zhou, Hao Pan, Lili Chen, Yiyuan Kang, Longquan Shao   +9 more
wiley   +1 more source

Decorin and Right Ventricular Failure in Pulmonary Hypertension: A Proteoglycan Controlling TGF-β Signaling in the Heart. [PDF]

JACC Basic Transl Sci
Schäfer K.
europepmc   +1 more source

Association of UCMA With Cartilage Pathogenesis and Inflammation in Patients With Rheumatoid Arthritis: A Novel Biomarker

Journal of Clinical Laboratory Analysis, EarlyView.
The study of 98 RA patients and 24 healthy controls found significantly higher serum levels of UCMA, COMP, TNF‐α, and IL‐6 in RA patients. ROC curve analysis showed that these markers could differentiate RA from healthy controls. UCMA correlates with inflammation and cartilage degeneration, suggesting its potential as a diagnostic marker.
Münteha Nur Sonuç Karaboğa, Hamza Malik Okuyan, Serdar Dogan, Hamdi Oguzman, Gezmiş Kimyon   +4 more
wiley   +1 more source

Dual targeting NG2 and GD3A using Mab-Zap immunotoxin results in reduced glioma cell viability in vitro [PDF]

, 2015
Ashkan, Keyoumars, Butt, Arthur M., Fillmore, Helen L., Higgins, Samantha C., Pilkington, Geoffrey J.   +4 more
core   +1 more source

Relapsing Polychondritis Associated With Thyroid Carcinoma: A First Malagasy Case. [PDF]

Case Rep Otolaryngol
Rakotonirainy OH, Andrianiaina MO, Rakotonirina LN, Ratovonjanahary V, Rabenja Rapelanoro F.   +4 more
europepmc   +1 more source

Telemedicine‐based diagnosis and management of ocular chemical injury in a remote setting: A case report

Journal of General and Family Medicine, EarlyView.
Abstract Ocular chemical injuries require immediate diagnosis and treatment, posing challenges in remote regions. We report a case of mild chemical injury caused by an alkali chemical injury, successfully diagnosed and managed using telemedicine. A primary care physician utilized a smartphone‐based anterior segment imaging system (Smart Eye Camera ...
Eisuke Shimizu, Hiroki Nishimura, Rohan Jeetendra Khemlani, Shintaro Nakayama, Keitaro Suzuki, Katsuya Sato   +5 more
wiley   +1 more source

Molecular Aspects of Cartilage Microfracturation: Rehabilitation Insights. [PDF]

Orthop Rev (Pavia)
Kacprzak B, Stańczak M, Bielenda B, Yarmohammadi AA, Hagner-Derengowska M.   +4 more
europepmc   +1 more source

Proteomics Reveals Increased Periostin in Synovial Fluid From Canine and Human Anterior Cruciate Ligament Injury

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Posttraumatic osteoarthritis (PTOA) is a common sequela to anterior cruciate ligament (ACL) injury in humans and dogs. Identification of conserved targets between species may hasten biomarker identification and therapeutic development. To identify differentially regulated synovial fluid (SF) proteins in ACL injury, SF samples were collected ...
Sydney J. Womack, Camila B. Carballo, Erica J. Secor, Scott A. Rodeo, Heidi L. Reesink   +4 more
wiley   +1 more source

Evolutionary origin of lubricated joints at the dawn of jawed vertebrates. [PDF]

PLoS Biol
Crump JG.
europepmc   +1 more source

Pain Assessment in Osteoarthritis: Present Practices and Future Prospects Including the Use of Biomarkers and Wearable Technologies, and AI‐Driven Personalized Medicine

Journal of Orthopaedic Research, EarlyView.
ABSTRACT Osteoarthritis (OA) is a highly prevalent chronic joint disorder affecting ~600 million individuals worldwide and is characterized by complex pain mechanisms that significantly impair patient quality of life. Challenges exist in accurately assessing and measuring pain in OA due to variations in pain perception among individuals and the ...
Shujaa T. Khan, Nick Huffman, Xiaojuan Li, Anukriti Sharma, Carl S. Winalski, Eric T. Ricchetti, Kathleen Derwin, Suneel S. Apte, Daniel Rotroff, Carl Y. Saab, Nicolas S. Piuzzi   +10 more
wiley   +1 more source