Results 201 to 210 of about 117,764 (297)

Characterization of Ovine Intervertebral Disc Health Across the Lifespan: Relationships Between Quantitative MRI, Radiological, Histological, Biochemical, and Biomechanical Assessments. [PDF]

JOR Spine
Yusuf Y, Abbott RE, Buko EO, Chase KL, Falck AL, Pendleton D, McDermott KA, Armstrong AR, Bradley EW, Johnson CP, Ellingson AM.   +10 more
europepmc   +1 more source

An unusual presentation of osteochondrosis in the elbows and tarsi of a Friesian colt

Equine Veterinary Education, EarlyView.
Summary This case report describes the clinical, diagnostic imaging results and post‐mortem findings in a foal that underwent reassessment following surgical management of angular limb deformities (ALD) and acute onset of gait abnormalities. Upon presentation, the foal showed an abnormal stiff gait characterised by bilateral medial limb collapse during
A. Torrent‐Crosa, A. Merchán‐Muñoz, C. Co, E. Borkowski   +3 more
wiley   +1 more source

T Cell Activation Induces Synthesis of CD47 Proteoglycan Isoforms and Their Release in Extracellular Vesicles. [PDF]

Int J Mol Sci
Kaur S, Kuznetsova SA, Sipes JM, Singh SP, Villasmil R, Roberts DD.   +5 more
europepmc   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

The FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

A proteoglycan-based topical treatment for hair greying: in vitro antioxidant and pro-melanogenic effects. [PDF]

Front Med (Lausanne)
Vega Diez D, Arias EM, Floriach N, Bravo E.   +3 more
europepmc   +1 more source

A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer

The FEBS Journal, EarlyView.
Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou, Sylvia Mangani, Spyros Kremmydas, Nikolaos E. Koletsis, Nikos K. Karamanos   +4 more
wiley   +1 more source

The Molecular Neurobiology of NG2-Expressing Glial Cells in Cerebral Small Vessel Disease Pathogenesis. [PDF]

Mol Neurobiol
Hein ZM, Ossama Zakareia Sayed Ahmed Abdelrazek A, Bilal Ahmed Shahbaz S, Che Mohd Nassir CMN.   +3 more
europepmc   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Chondroitin sulfate proteoglycan 4 (CSPG4) overexpression as an oncogenic driver and prognostic marker for unfavorable outcomes in hepatocellular carcinoma. [PDF]

World J Surg Oncol
Ren C, Yan F, Xiang H, Hong T, Mierxiati A, Zhang L, Wang M, Wang C.   +7 more
europepmc   +1 more source