ABSTRACT Osteoarthritis (OA) is a common degenerative joint disease characterized by chondrocyte dysfunction. In this study, we explored the function and mechanism of ubiquitin‐specific protease 7 (USP7) in chondrocyte ferroptosis in OA. The USP7, TRPV1, collagen II, and GPX4 levels in knee joint tissue were detected using immunohistochemistry ...
Jun Li, Ding Chen, Wei‐Ye Zhong
wiley +1 more source
Bioengineered Tricomposite Hydrogel Enhances Chondrogenic Phenotype and Hyaline Matrix Formation in Human Chondrocytes. [PDF]
Rojas-Murillo A +8 more
europepmc +1 more source
Abstract Purpose Anterior cruciate ligament (ACL) injury and reconstruction significantly increase the risk of knee osteoarthritis (OA). Biomechanical alterations during walking are frequently suggested contributors to OA development. This systematic review aims to determine the association between walking gait biomechanical changes following ACL ...
Jérôme Riera +4 more
wiley +1 more source
Author Correction: Inhibition of cyclooxygenase-2 activity in subchondral bone modifies a subtype of osteoarthritis. [PDF]
Tu M +12 more
europepmc +1 more source
Immunological Evaluation of PLLA/GO Scaffolds in Goat Mandibular Bone Regeneration
PLLA/GO scaffolds interact with bone tissue by modulating the immune response and promoting regeneration in goat mandibles. Histological and immunohistochemical analyses reveal progressive tissue organization, mineral deposition, osteoblastic activity, and angiogenesis over time.
Thamires Santos‐Silva +10 more
wiley +1 more source
Icosapent ethyl-induced lipoprotein remodeling and its impact on cardiovascular disease risk markers in normolipidemic individuals. [PDF]
Äikäs L +9 more
europepmc +1 more source
Protein glycosylation in lung cancer from a mass spectrometry perspective
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi +2 more
wiley +1 more source
Degenerative Disease of Intervertebral Disc: A Narrative Review of Pathogenesis, Clinical Implications and Therapies. [PDF]
Gradisnik L +3 more
europepmc +1 more source
Advancements in Mass Spectrometry‐Based Glycomics in Food and Nutritional Science
ABSTRACT This review highlights advancements in mass spectrometry (MS)‐based glycomics in food and nutritional science. Carbohydrates, which are vital for human health, exhibit complex structures, making their analysis challenging. MS has become an indispensable tool for elucidating the structures of carbohydrates, including glycans, through soft ...
JaeHui Song +3 more
wiley +1 more source

