Results 111 to 120 of about 152,765 (288)

Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli   +6 more
wiley   +1 more source

Plaque‐Targeted Delivery of Fluoride‐Free MXene Nanozyme for Alleviating Atherosclerosis via Sonocatalytic Therapy

open access: yesAdvanced Materials, EarlyView.
This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and anti­inflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai   +6 more
wiley   +1 more source

Chemoselective Characterization of New Extracellular Matrix Deposition in Bioengineered Tumor Tissues

open access: yesAdvanced Materials, EarlyView.
Understanding the bi‐directional crosstalk between cells and their surrounding extracellular matrix (ECM) is critical for tissue engineering. This study presents a chemoselective strategy for proteomic profiling of newly deposited ECM from resident cells.
Zihan Ling   +9 more
wiley   +1 more source

Elastic Energy Storage in Biological Materials: Internal Stresses and Their Functionality

open access: yesAdvanced Materials, EarlyView.
Harnessing and storing internally generated elastic energy is a clever strategy by biological materials to perform functions like shape transformation, movement, and predation. This review explores how biological systems manipulate mechanisms like atomic or protein integration into minerals, protein conformational shifts, phase transitions, and osmotic
Shahrouz Amini   +3 more
wiley   +1 more source

EFFECTS OF MODULATING NF ΚB AND NRF2 SIGNALING PATHWAYS ON THE DEPOLYMERIZATION OF CONNECTIVE TISSUE BIOPOLYMERS IN THE RAT SMALL INTESTINE UNDER SURGICAL TRAUMA FOLLOWING SINGLE PROLONGED STRESS

open access: yesПроблеми екології та медицини
This study aimed to investigate the effects of ammonium pyrrolidinedithiocarbamate (an inhibitor of NF κB activation) and sulforaphane (an inducer of the Nrf2/antioxidant response element (ARE) signaling pathway) on the depolymerization processes of ...
R.M. Ryabushko   +2 more
doaj   +1 more source

The Corneoscleral Shell of the Eye: an Age-Related Analysis of Structural Biomechanical Properties. Literature review

open access: yesOftalʹmologiâ, 2016
Structural biomechanical properties of the ocular corneoscleral shell largely determine its anatomic and optical parameters and its supporting and protective function.
E. N. Iomdina   +4 more
doaj   +1 more source

Engineering Aging: Approaches to Model and Deconstruct Biological Complexity

open access: yesAdvanced Materials, EarlyView.
The macro‐experiences of aging are the result of an accumulation of micro‐changes that occur over time. Abstract The disparity between the global increase in life expectancy and the steady decline in health outcomes with age has been a major driver for developing new ways to research aging.
Habib Joukhdar   +7 more
wiley   +1 more source

Apolipoprotein A-I mimetic peptide 4F blocks sphingomyelinase-induced LDL aggregation

open access: yesJournal of Lipid Research, 2015
Lipolytic modification of LDL particles by SMase generates LDL aggregates with a strong affinity for human arterial proteoglycans and may so enhance LDL retention in the arterial wall.
Su Duy Nguyen   +11 more
doaj   +1 more source

The monoclonal antibody nBT062 conjugated to maytansinoids has potent and selective cytotoxicity against CD138 positive multiple myeloma cells _in vitro_ and _in vivo_ [PDF]

open access: yes, 2008
CD138 (Syndecan1) is highly expressed on multiple myeloma (MM) cells. In this study, we examined the anti-MM effect of murine/human chimeric CD138-specific monoclonal antibody (mAb) nBT062 conjugated with highly cytotoxic maytansinoid derivatives _in ...
Benjamin Dä   +20 more
core   +1 more source

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