Results 151 to 160 of about 100,368 (249)

Engineered 3D Fibronectin‐Based Environments Modulate the Pathogenic Profile of Arthritic Synovial Fibroblasts

Advanced NanoBiomed Research, EarlyView.
Fibroblast behavior is shaped by the surrounding microenvironment, yet conventional culture systems often fail to capture disease‐relevant phenotypes. Here, platform‐dependent responses of healthy and arthritic synovial fibroblasts are examined across 2D and 3D culture systems. Distinct inflammatory and proliferative signatures emerge, highlighting how
Aneesah Khan, Piaopiao Pan, Yanling Lan, Çağlar Çi̇l, Julia Isakova, Yilin Wang, Theodora Rogkoti, Thanutchaporn Sartyoungkul, James F. C. Windmill, Jonathan William, Manuel Salmeron‐Sanchez, Margaret H. Harnett, Oana Dobre, Miguel A. Pineda   +13 more
wiley   +1 more source

Proteoglycan-Mimetic Bottle-Brush Polymer Brushes for Osteoarthritis Therapy: Lubrication Enhancement and Multifunctional Disease Modulation. [PDF]

Macromol Rapid Commun
Chen F, Zhao L, Zhang Y, Qin C, Liu Y.
europepmc   +1 more source

Biomimetic Nanofiber Scaffold Coated With Acellular Matrices for Uterine Myometrial Tissue Engineering

Advanced NanoBiomed Research, EarlyView.
Schematic representation of acellular matrix generation from human uterine fibroblast cells, coating on polycaprolactone electrospun nanofibers, and subsequent in vitro and in vivo characterization. A tissue‐engineered scaffold tailored for uterine myometrium‐specific regeneration is designed. The electrospinning technique was used to fabricate aligned
Srividya Hanuman, Shripad S. Hebbar, Rishikesh Balvalli, Manasa Nune   +3 more
wiley   +1 more source

Stenosis in Mature Arteriovenous Fistulas Characterized by Contractile Smooth Muscle Cells and Versican. [PDF]

Kidney Int Rep
Zhang Y, Elzinad N, Lotfollahzadeh S, Lazowski A, Elsadawi M, Yin W, Belghasem M, Bharti J, Idrees N, Zavarro C, Shazly T, Jaberi A, Francis J, Farber A, Vazquez-Padron R, Dember LM, Siracuse J, Kolachalama VB, Chitalia VC.   +18 more
europepmc   +1 more source

Biomimetic Nanomedicine for Aging‐Impaired Bone Regeneration: From Microenvironmental Dysfunction to Precision Therapeutics

Advanced NanoBiomed Research, EarlyView.
Aging disrupts the cellular, immune, vascular, and neural processes required for bone regeneration. This review connects these pathological barriers with biomimetic nanomedicine design, highlighting strategies for cellular rejuvenation, immune modulation, vascular regeneration, and neuro–bone coupling.
Zeyu Wang, He Zhang, Simo Liu, Rui Wang, Yiran Wei, Kailu Zheng, Yanming Guo, Min Li, Dian Yuan, Yuxin Liu, Lifang Feng, Yongping Ma, Yan Liu   +12 more
wiley   +1 more source

The role of nervous system extracellular matrix remodeling in chronic pain. [PDF]

Pain
Alhamwi A, Anits E, Krock E.
europepmc   +1 more source

Aortic Stenosis Hyalectan Remodeling Revealed by Proteomics and Glycoproteomics. [PDF]

Arterioscler Thromb Vasc Biol
Yin S, Mayr U, Barallobre-Barreiro J, Duregotti E, Barton AK, Bing R, Markose D, Yin X, Sarathchandra P, Singh B, Lin WY, Fava M, Schmidt LE, Baig F, Shah AM, Theofilatos K, Latif N, Hengstenberg C, Radovits T, Merkely B, Henderson NC, Dweck MR, Mayr M.   +22 more
europepmc   +1 more source

Structure and metabolism of bovine aortic proteoglycans

Although a number of studies of arterial glycosaminoglycans have been carried out, there is comparatively little information available regarding the native state in which these glycosaminoglycans occur, namely covalently bound to protein to form ...
Murray, Eileen
core  

Composition and Function of Decellularized Human Lung Extracellular Matrix from Congenital Pulmonary Airway Malformation. [PDF]

J Clin Med
Li Y, Yang P, Yuan M, Zhu X, Mao S, Yang Y, Yao M, Chen F, Zhou Y, Bao J, Xu C, Li Y.   +11 more
europepmc   +1 more source

Heparan Sulfate Proteoglycans: Master Regulators of Cellular Signaling, Tissue Development, and Neural Function. [PDF]

J Neurosci Res
Melrose J.
europepmc   +1 more source