Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik +3 more
wiley +1 more source
Exploring the application of shear stress in erectile dysfunction. [PDF]
Deng WJ +4 more
europepmc +1 more source
ABSTRACT Purpose To develop and validate an accelerated phase‐modulated ultrashort echo time (PM‐UTE) sequence for volumetric T2 and adiabatic T1ρ (AdiabT1ρ) mapping of both short‐ and long‐T2 tissues in the knee joint. Methods The proposed method estimates and removes the T1‐dependent component from a single reference acquisition, eliminating repeated
Jiyo S. Athertya +7 more
wiley +1 more source
Determination of Dental Lesions in Dairy Cattle and Immunochemical Detection of the Biomarker Decorin in Gingival Crevicular Fluid of Dairy Cattle. [PDF]
Avci N.
europepmc +1 more source
Innate immunity shapes the persistent transmission of plant viruses by insect vectors
In this review, we focus on two key aspects of the virus–vector interplay: (1) persistently transmitted viruses utilize host factors to overcome transmission barriers; and (2) molecular recognition activates antiviral immunity and subsequent viral counter‐defense. Understanding these interactions offers critical insights for developing novel strategies
Gang Lu, Chuanxi Zhang, Junmin Li
wiley +1 more source
Heparan Sulfates Regulate Vascular Reactivity in Syndecan 1 Knockout Mice. [PDF]
Potje SR +3 more
europepmc +1 more source
Migrasomes, Matrix‐Bound Nanovesicles, and More: Messengers in the Matrix
ABSTRACT Extracellular vesicles (EVs) and particles (EPs) are diverse micro‐ and nanoparticles that circulate in bodily fluids and can attach to, or be deposited onto, the extracellular matrix (ECM) and other surfaces. To date, the nomenclature and classification of matrix‐bound or matrix‐associated EVs and EPs (MEVPs) have been unclear, largely due to
Anna V. Kolesov +3 more
wiley +1 more source
Decoding Fibroblast Diversity Associated with the Postnatal Loss of Cardiac Regenerative Capacity. [PDF]
Aghagolzadeh P +5 more
europepmc +1 more source
Proteomic Profiling of Myofiber Repair Annexins and Their Role in Duchenne Muscular Dystrophy
ABSTRACT Myofiber regeneration and membrane repair play crucial roles in maintaining the continuous physiological functioning of the neuromuscular system. A swift and efficient repair mechanism enables the rapid restoration of sarcolemmal integrity following cellular impairment in damaged skeletal muscles.
Paul Dowling +6 more
wiley +1 more source

