Results 11 to 20 of about 152,765 (288)
Atherosclerosis: from lipid-lowering and anti-inflammatory therapies to targeting arterial retention of ApoB-containing lipoproteins [PDF]
Frontiers in ImmunologyAtherosclerosis is a chronic inflammatory disease characterized by the accumulation of lipids, fibrous elements, and cellular debris in the blood vessels. The response-to-retention hypothesis, the leading theory on the pathogenesis of this cardiovascular
Gala Araujo +5 more
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Poultry Science, 2023 : This study aimed to assess the influence of glycosaminoglycan (chondroitin and glucosamine sulfates) supplementation in the diet of broilers on the expression of matrix metallopeptidase 9 (MMP-9) and metallopeptidase inhibitor 2 (TIMP-2) genes, the ...
Julyana M.S. Martins +8 more
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Pharmaceuticals, 2022 Cisplatin-based chemotherapy has been effectively used to treat oral cancer, but treatment often fails owing to the development of drug resistance. However, the important gene expression alterations associated with these resistances remain unclear.
Hyeong Sim Choi +2 more
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Diagnostics, 2022 The aim of this study was the preliminary assessment of a new cationic contrast agent, the CA4+, via the analysis of spatial distribution in cartilage of ex vivo bovine samples, at micrometer and millimeter scale.
Simone Fantoni +11 more
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Proteoglycans as Mediators of Cancer Tissue Mechanics
Frontiers in Cell and Developmental Biology, 2020 Proteoglycans are a diverse group of molecules which are characterized by a central protein backbone that is decorated with a variety of linear sulfated glycosaminoglycan side chains.
Anna Barkovskaya +8 more
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Lumican in Carcinogenesis—Revisited
Biomolecules, 2021 Carcinogenesis is a multifactorial process with the input and interactions of environmental, genetic, and metabolic factors. During cancer development, a significant remodeling of the extracellular matrix (ECM) is evident.
Eirini-Maria Giatagana +4 more
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Differentiation of Human Embryonic Stem Cells into Cells with Corneal Keratocyte Phenotype [PDF]
, 2013 Corneal transparency depends on a unique extracellular matrix secreted by stromal keratocytes, mesenchymal cells of neural crest lineage. Derivation of keratocytes from human embryonic stem (hES) cells could elucidate the keratocyte developmental pathway
Chan, AA +8 more
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Frontiers in Medicine, 2023 BackgroundCalcineurin inhibitors (CNIs) are associated with nephrotoxicity, endothelial cell dysfunction, and thrombotic microangiopathy (TMA). Evolving evidence suggests an important role for complement dysregulation in the pathogenesis of CNI-induced ...
Chia Wei Teoh +25 more
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Esophageal Cancer Development: Crucial Clues Arising from the Extracellular Matrix
Cells, 2020 In the last years, the extracellular matrix (ECM) has been reported as playing a relevant role in esophageal cancer (EC) development, with this compartment being related to several aspects of EC genesis and progression.
Antonio Palumbo +6 more
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Nondestructive fluorescence lifetime imaging and time-resolved fluorescence spectroscopy detect cartilage matrix depletion and correlate with mechanical properties [PDF]
European Cells & Materials, 2018 Tissue engineers utilize a battery of expensive, time-consuming and destructive techniques to assess the composition and function of engineered tissues.
AK Haudenschild +6 more
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