Results 191 to 200 of about 132,430 (262)

Neutrophil Elastase Targets Select Proteins on Human Blood-Monocyte-Derived Macrophage Cell Surfaces. [PDF]

Int J Mol Sci
Ahmed NT, Kummarapurugu AB, Zheng S, Bulut G, Kang L, Batheja A, Hawkridge A, Voynow JA.   +7 more
europepmc   +1 more source

Single Extracellular Vesicle Profiling to Define Brain Specific Traumatic Brain Injury Induced Neuro‐Inflammation

Small Methods, EarlyView.
A highly innovative and implementable diagnostic tool for profiling microenvironmental perturbations in TBI patients by analyzing sEVs derived from glial cells circulating in the blood. This device provides a window into the injured brain and identifies neuroinflammatory signals, potentially serving as a platform for detecting highly specific brain ...
Zhen Zhang, Richard J Lobb, Rebecca E Lane, Xuan Vinh To, Xueming Niu, Fiach Antaw, Giovanni Pietrogrande, Craig Winter, Alain Wuethrich, Fatima Nasrallah, Matt Trau   +10 more
wiley   +1 more source

Ephrin-B1 regulates cell surface residency of heparan sulfate proteoglycans (HSPGs) and complexes with the HSPG CD44V3-10 and fibroblast growth factor receptors. [PDF]

Glycobiology
Prydz K, Simm R, Davydova E, Aasheim HC.
europepmc   +1 more source

Kartogenin‐Loaded Aminated Hollow Mesoporous Prussian Blue Nanozyme‐Reinforced Hydrogel Remodels the Senescent Microenvironment via Reactive Oxygen Species Scavenging and Stimulator of Interferon Genes Inhibition to Promote Cartilage Regeneration

Small Structures, EarlyView.
This study successfully develops an injectable, dual‐function nanocomposite hydrogel comprising kartogenin‐loaded aminated hollow mesoporous Prussian blue (NH2‐HMPB) nanozyme (termed NH@K nanozyme) and hyaluronic acid methacrylate (HAMA). NH@K nanozyme rejuvenates the senescent microenvironment by scavenging reactive oxygen species and inhibiting ...
Shu‐Hang He, Zhi‐Han Shen, Ren Zhang, Po‐Lin Liu, Xu‐Ran Li, Qing‐Song Deng, Yu‐Chen Zhang, Ang Wang, Xiao‐Qiu Dou, Shang‐Chun Guo, Shi‐Cong Tao   +10 more
wiley   +1 more source

Enhanced Adhesion of Mildly Positively Charged Vesicles to Endothelial Cells with Shed Glycocalyx. [PDF]

ACS Omega
Sirch MM, Wörle D, Huber MG, Westerhausen C.   +3 more
europepmc   +1 more source

Glycopattern comparison of sperm and exosomes from conventional in vitro fertilization and rescue intracytoplasmic sperm injection: Enhancing sperm motility through exosome‐mediated glycan modulation

VIEW, EarlyView.
Infertility is a global concern, with male factors contributing to nearly half of cases. This study compared glycopatterns of sperm and sperm‐derived exosomes from conventional IVF and rescue ICSI (RICSI) patients, revealing key differences in glycan expression.
Muhammad Anas Ramzan, Zhedong Yang, Li Cao, Jinyuan Zhang, Fei Wu, Miaomiao Xin, Bo Guo, Lumin Wang, Lingyu Zhao, Yannan Qin, Chengcheng Liu   +10 more
wiley   +1 more source

Stem cell therapy for intervertebral disc degeneration: Clinical progress with exosomes and gene vectors. [PDF]

World J Stem Cells
Li ZP, Li H, Ruan YH, Wang P, Zhu MT, Fu WP, Wang RB, Tang XD, Zhang Q, Li SL, Yin H, Li CJ, Tian YG, Han RN, Wang YB, Zhang CJ.   +15 more
europepmc   +1 more source

Single‐cell spatial transcriptomic sequencing and machine learning models uncover molecular mechanisms and diagnostic biomarkers of Peyronie's disease formation in rats

VIEW, EarlyView.
Peyronie's disease (PD) is a common male reproductive system disorder. The exact etiology of PD remains unclear. This study aimed to investigate molecular and cellular changes in PD using single‐cell spatial transcriptomics. Abstract Peyronie's disease (PD), commonly known as penile induration, is a prevalent male reproductive system disorder with ...
Keyuan Lou, Qiancheng Mao, Junpeng Chi, Jiankun Zhang, Hao Guo, Jitao Wu, Yuanshan Cui   +6 more
wiley   +1 more source

Obesity Alters the Vascular Morphology and VEGF‐A Signaling in Adipose Tissue

FASEB BioAdvances, EarlyView.
Obesity alters cell geometry and vessel morphology in mice adipose tissue by increasing adipocyte size by 78% and reducing vessel density by 51%, while vessel size and capillary basement membrane thickness remain unchanged. Obesity also affects angiogenesis, which is mediated by vascular endothelial growth factor (VEGF) binding kinetics.
Yunjeong Lee, Keith Lionel Tukei, Yingye Fang, Shobhan Kuila, Xinming Liu, Princess I. Imoukhuede   +5 more
wiley   +1 more source

Zebrafish arterial valve development occurs through direct differentiation of second heart field progenitors. [PDF]

Cardiovasc Res
Derrick CJ, Eley L, Alqahtani A, Henderson DJ, Chaudhry B.   +4 more
europepmc   +1 more source