Results 191 to 200 of about 189,785 (400)
The proteoglycan content and the axial periodicity of collagen in tendon [PDF]
, 1977 Gerald C. Gillard +4 more
openalex +1 more source
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
Proceedings of the National Academy of Sciences of the United States of America, 2013 Brandon B. Holmes +13 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study describes the creation of injectable Brachyury (Bry) mRNA‐loaded Fucoidan‐functionalized GelMA hydrogel microspheres (BLNP@GF). These microspheres efficiently suppress inflammation, enhance extracellular matrix (ECM) synthesis in degenerated nucleus pulposus cells, and mitigate intervertebral disc degeneration (IVDD) in rat models.
Yuhao Gong +12 more
wiley +1 more source
Electron microscopic studies of proteoglycan aggregates from bovine articular cartilage.
, 1975 Lynn Rosenberg +2 more
openalex +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2013 H. Christianson +4 more
semanticscholar +1 more source
Advanced Science, EarlyView.Upregulated glycosyltransferase GALNT9 in neuroendocrine (NE) carcinomas increases O‐GalNAc glycosylation on cell membrane proteins, particularly Annexin‐A2 (ANXA2). Elevated O‐GalNAc glycan induces the binding of NE cancer cells to mannose binding lectin 2 (MBL2), activating the MBL‐MBL associated serine protease (MBL‐MASP) complement pathway in the ...
Xinyu Chen +24 more
wiley +1 more source
Advanced Science, EarlyView.β‐Mangostin alleviates intervertebral disc degeneration through dual modulation of macrophage polarization and the TET2‐Prkcg axis in nucleus pulposus cells. Abstract Intervertebral disc degeneration (IDD) induced lower back pain is a main cause of disability, resulting in a substantial workforce loss worldwide and placing a substantial burden on the ...
Xiangzhen Kong +15 more
wiley +1 more source
Advanced Science, EarlyView.Targeting eRNAs from TNFα‐associated super‐enhancers with ASOs effectively reduces TNFα expression and inflammatory responses in both mouse models and patient‐derived immune cells. The conserved nature of these regulatory regions between species highlights the potential of eRNA‐targeted approaches as a therapeutic strategy for chronic inflammatory ...
Minjeong Cho +12 more
wiley +1 more source
The Action of Cathepsin D in Human Articular Cartilage on Proteoglycans [PDF]
, 1973 Asher I. Sapolsky +3 more
openalex +1 more source