Glycosaminoglycans in the human cornea: age-related changes [PDF]
, 2015 AIM: To investigate possible age-related changes in glycosaminoglycans (GAGs) in the human cornea. The substances today called GAGs were previously referred to as mucopolysaccharides.
Anello, Giulia +6 more
core +2 more sources
BMC Cancer, 2009 Background Salivary adenoid cystic carcinoma (SACC) is one of the most common malignancies of salivary gland. Recurrence or/and early metastasis is its biological properties.
Li Hexiang +5 more
doaj +1 more source
Proteoglycan desulfation: a critical step in oncogenesis?
Frontiers in Bioscience-Landmark, 2020 Proteoglycans are essential constituents of tissue- and organ microenvironments, modulating both the structural scaffolds that surround cells as well as signaling cues that determine cellular phenotype.
Vishal Singh, Ramray Bhat
doaj +1 more source
Poultry Science, 2023 : This study aimed to assess the influence of glycosaminoglycan (chondroitin and glucosamine sulfates) supplementation in the diet of broilers on the expression of matrix metallopeptidase 9 (MMP-9) and metallopeptidase inhibitor 2 (TIMP-2) genes, the ...
Julyana M.S. Martins +8 more
doaj +1 more source
Charge Characteristics of Agouti-Related Protein Implicate Potent Involvement of Heparan Sulfate Proteoglycans in Metabolic Function. [PDF]
, 2019 The endogenous melanocortin peptide agouti-related protein (AgRP) plays a well-known role in foraging, but its contribution to metabolic regulation is less understood.
Chen, Jihuan +9 more
core +1 more source
Nondestructive fluorescence lifetime imaging and time-resolved fluorescence spectroscopy detect cartilage matrix depletion and correlate with mechanical properties [PDF]
European Cells & Materials, 2018 Tissue engineers utilize a battery of expensive, time-consuming and destructive techniques to assess the composition and function of engineered tissues.
AK Haudenschild +6 more
doaj +1 more source
Increased expression of aggrecan and biglycan mRNA in Achilles tendinopathy [PDF]
, 2006 To determine the expression of mRNA encoding the proteoglycans aggrecan, versican, biglycan and decorin in mid-tendon samples of chronic painful Achilles tendinopathy and ruptured Achilles tendons, compared with normal tendons.
Corps, AN +5 more
core +1 more source
RNA-Seq identifies SPGs as a ventral skeletal patterning cue in sea urchins [PDF]
, 2016 The sea urchin larval skeleton offers a simple model for formation of developmental patterns. The calcium carbonate skeleton is secreted by primary mesenchyme cells (PMCs) in response to largely unknown patterning cues expressed by the ectoderm.
Bardot, Evan +26 more
core +1 more source
Sonic Hedgehog Is a Member of the Hh/DD-Peptidase Family That Spans the Eukaryotic and Bacterial Domains of Life. [PDF]
, 2018 Sonic Hedgehog (Shh) coordinates Zn2+ in a manner that resembles that of peptidases. The ability of Shh to undergo autoproteolytic processing is impaired in mutants that affect the Zn2+ coordination, while mutating residues essential for catalytic ...
Roelink, Henk
core +3 more sources
Synovial joint lubrication – does nature teach more effective engineering lubrication strategies? [PDF]
, 2007 Nature shows numerous examples of systems which show energy efficiency, elegance in their design and optimum use of materials. Biomimetics is an emerging field of research in engineering and successes have been documented in the diverse fields of ...
Liskiewicz, T. +3 more
core +1 more source