Results 41 to 50 of about 189,785 (400)
Versican splice variant messenger RNA expression in normal human Achilles tendon and tendinopathies [PDF]
, 2004 Versican is the principal large proteoglycan expressed in mid-tendon, but its role in tendon pathology is unknown. Our objective was to define the expression of versican isoform splice variant messenger ribonucleic acid (mRNA) in normal Achilles tendons,
Corps, AN +6 more
core +2 more sources
Müller glia activation in response to inherited retinal degeneration is highly varied and disease-specific [PDF]
, 2015 Despite different aetiologies, most inherited retinal disorders culminate in photoreceptor loss, which induces concomitant changes in the neural retina, one of the most striking being reactive gliosis by Müller cells.
Ali, RR +6 more
core +1 more source
Molecular BioSystems, 2012 Proteoglycans (PGs) are among the most structurally complex biomacromolecules in nature. They are present in all animal cells and frequently exert their critical biological functions through interactions with protein ligands and receptors. PGs are comprised of a core protein to which one or multiple, heterogeneous, and polydisperse glycosaminoglycan ...
Lingyun, Li +2 more
openaire +2 more sources
Intracellular proteoglycans [PDF]
Biochemical Journal, 2004 Proteoglycans (PGs) are proteins with glycosaminoglycan chains, are ubiquitously expressed and have a wide range of functions. PGs in the extracellular matrix and on the cell surface have been the subject of extensive structural and functional studies.
Svein Olav, Kolset +2 more
openaire +2 more sources
Heparan sulfate proteoglycans present PCSK9 to the LDL receptor
Nature Communications, 2017 Coronary artery disease is the main cause of death worldwide and accelerated by increased plasma levels of cholesterol-rich low-density lipoprotein particles (LDL).
Camilla Gustafsen +13 more
semanticscholar +1 more source
Synovial joint lubrication – does nature teach more effective engineering lubrication strategies? [PDF]
, 2007 Nature shows numerous examples of systems which show energy efficiency, elegance in their design and optimum use of materials. Biomimetics is an emerging field of research in engineering and successes have been documented in the diverse fields of ...
Liskiewicz, T. +3 more
core +1 more source
The podocyte and the proteoglycan [PDF]
American Journal of Physiology-Renal Physiology, 2016 proteoglycans (PGs) consist of a core protein and linear sugar side chains [glycosaminoglycans (GAGs)] attached to the core protein, e.g., agrin, perlecan, glypican, and syndecan. GAGs comprise repeating duplex sugar units made of an aminosugar (e.g., N -acetylglucosamine or N -acetylgalactosamine)
openaire +3 more sources
Could Biglycan be a biomarker of coronary artery disease? A pilot human study
Research in Cardiovascular Medicine, 2018 Background: Coronary artery calcification (CAC) is utilized as an important tool for the global risk assessment of cardiovascular events in individuals with intermediate risk.
Atefeh Rezapour +9 more
doaj +1 more source
Matrix Effectors in the Pathogenesis of Keratinocyte-Derived Carcinomas
Frontiers in Medicine, 2022 Basal cell carcinoma (BCC) and cutaneous squamous cell carcinoma (cSCC), referred to as keratinocyte carcinomas, are skin cancer with the highest incidence.
Rafaela-Maria Kavasi +12 more
doaj +1 more source
Proteoglycans in liver cancer.
World Journal of Gastroenterology, 2016 Proteoglycans are a group of molecules that contain at least one glycosaminoglycan chain, such as a heparan, dermatan, chondroitin, or keratan sulfate, covalently attached to the protein core.
Kornélia Baghy +3 more
semanticscholar +1 more source